Human DDB1- and CUL4-associated factor 6 (DCAF6) ELISA Kit

Este producto es parte de DCAF - DDB1 and CUL4 associated factor
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715€ (96 tests)

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935106861
info@markelab.com
name
Human DDB1- and CUL4-associated factor 6 (DCAF6) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx509775
tested applications
ELISA

Description

Human DDB1- and CUL4-associated factor 6 (DCAF6) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DDB1- and CUL4-associated factor 6 (DCAF6) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
DDB1- and CUL4-associated factor 6 (DCAF6)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Test Range
0.156 ng/ml - 10 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Form
Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-15 working days. The validity for this kit is 6 months.
Storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q58WW2
OMIM
610494
Alias
NRIP,ARCAP,IQWD1,PC326,MSTP055,Nuclear receptor interaction protein,IQ motif and WD repeat-containing protein 1,Androgen receptor complex-associated protein
Background
Elisa kits for DCAF6
Status
RUO
Note
Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

DDB1 and CUL4 associated factor 6 (DCAF6), also known as TCEB3C, acts as a substrate receptor for the CUL4-DDB1 E3 ubiquitin ligase complex and is involved in the regulation of transcriptional activity and cellular signaling. DCAF6 interacts with nuclear receptors and transcription factors, mediating their ubiquitination and subsequent degradation to modulate gene expression. It is particularly noted for its role in steroid hormone receptor signaling, where it interacts with androgen and glucocorticoid receptors, influencing hormone-responsive gene networks. DCAF6 is broadly expressed across tissues, with high relevance in hormonal regulation and stress responses. Its dysregulation has been associated with diseases such as cancer, where altered nuclear receptor signaling contributes to tumor progression. Research into DCAF6 continues to uncover its diverse roles in transcriptional regulation and its potential as a therapeutic target.

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