Human DDB1- and CUL4-associated factor 5 (DCAF5) ELISA Kit
715€ (96 tests)
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name
Human DDB1- and CUL4-associated factor 5 (DCAF5) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx509773
tested applications
ELISA
Description
Human DDB1- and CUL4-associated factor 5 (DCAF5) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DDB1- and CUL4-associated factor 5 (DCAF5) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | DDB1- and CUL4-associated factor 5 (DCAF5) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q96JK2 |
| OMIM | 603812 |
| Alias | BCRG2,BCRP2,WDR22,D14S1461E,WD repeat-containing protein 22,Breakpoint cluster region protein 2 |
| Background | Elisa kits for DCAF5 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DDB1 and CUL4 associated factor 5 (DCAF5), also known as WDR82, is a substrate receptor in the CUL4-DDB1 E3 ubiquitin ligase complex and is involved in various nuclear processes, including transcriptional regulation and epigenetic modification. DCAF5 contains WD40 repeats, which enable it to interact with histone-modifying enzymes and transcription factors, mediating the ubiquitination and degradation of these nuclear substrates. It has been implicated in histone methylation, particularly by interacting with methyltransferase complexes like SETD1A/B, playing a key role in chromatin remodeling and gene expression regulation. DCAF5 is ubiquitously expressed, and its function is critical for maintaining genomic stability and orchestrating cellular responses to environmental cues. Dysregulation of DCAF5 has been linked to abnormal gene expression patterns and cancer, emphasizing its importance in both normal physiology and disease.
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