Human DDB1- and CUL4-associated factor 4 (DCAF4) ELISA Kit
715€ (96 tests)
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935106861
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name
Human DDB1- and CUL4-associated factor 4 (DCAF4) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx509772
tested applications
ELISA
Description
Human DDB1- and CUL4-associated factor 4 (DCAF4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DDB1- and CUL4-associated factor 4 (DCAF4) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | DDB1- and CUL4-associated factor 4 (DCAF4) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8WV16 |
| OMIM | 616372 |
| Alias | WDR21,WDR21A,WD repeat-containing protein 21A |
| Background | Elisa kits for DCAF4 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DDB1 and CUL4 associated factor 4 (DCAF4) is a member of the WD40 protein family that acts as a substrate receptor within the CUL4-DDB1 E3 ubiquitin ligase complex. DCAF4 is critical for identifying and binding specific proteins to facilitate their ubiquitination and subsequent degradation via the proteasome. The protein’s WD40 domains are key to its substrate specificity and interactions with the E3 ligase machinery. DCAF4 is widely expressed across various tissues, with notable involvement in processes such as cell cycle regulation, DNA damage repair, and transcriptional control. Its functions are thought to contribute to maintaining genomic stability and responding to cellular stress. Research has suggested a possible link between DCAF4 dysfunction and disease states, including cancer, due to its role in regulating protein turnover and signaling pathways. The identification of its substrate proteins will further clarify its role in both normal cellular processes and pathological conditions.
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