Human DDB1- and CUL4-associated factor 4 (DCAF4) ELISA Kit

Este producto es parte de DCAF - DDB1 and CUL4 associated factor
Human DDB1- and CUL4-associated factor 4 (DCAF4) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for DCAF4

proveedor

Abbexa

reference

abx509772

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human DDB1- and CUL4-associated factor 4 (DCAF4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DDB1- and CUL4-associated factor 4 (DCAF4) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.


Background

DDB1 and CUL4 associated factor 4 (DCAF4) is a member of the WD40 protein family that acts as a substrate receptor within the CUL4-DDB1 E3 ubiquitin ligase complex. DCAF4 is critical for identifying and binding specific proteins to facilitate their ubiquitination and subsequent degradation via the proteasome. The protein’s WD40 domains are key to its substrate specificity and interactions with the E3 ligase machinery. DCAF4 is widely expressed across various tissues, with notable involvement in processes such as cell cycle regulation, DNA damage repair, and transcriptional control. Its functions are thought to contribute to maintaining genomic stability and responding to cellular stress. Research has suggested a possible link between DCAF4 dysfunction and disease states, including cancer, due to its role in regulating protein turnover and signaling pathways. The identification of its substrate proteins will further clarify its role in both normal cellular processes and pathological conditions.

Características del producto

category

ELISA Kits


immunogen target

DDB1- and CUL4-associated factor 4 (DCAF4)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.


size 1

96 tests


alias

WDR21,WDR21A,WD repeat-containing protein 21A


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

DCAF4


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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