Human DDB1- and CUL4-associated factor 4 (DCAF4) ELISA Kit

Pida mas información
935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for DCAF4
proveedor
Abbexareference
abx509772Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human DDB1- and CUL4-associated factor 4 (DCAF4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DDB1- and CUL4-associated factor 4 (DCAF4) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Background
DDB1 and CUL4 associated factor 4 (DCAF4) is a member of the WD40 protein family that acts as a substrate receptor within the CUL4-DDB1 E3 ubiquitin ligase complex. DCAF4 is critical for identifying and binding specific proteins to facilitate their ubiquitination and subsequent degradation via the proteasome. The protein’s WD40 domains are key to its substrate specificity and interactions with the E3 ligase machinery. DCAF4 is widely expressed across various tissues, with notable involvement in processes such as cell cycle regulation, DNA damage repair, and transcriptional control. Its functions are thought to contribute to maintaining genomic stability and responding to cellular stress. Research has suggested a possible link between DCAF4 dysfunction and disease states, including cancer, due to its role in regulating protein turnover and signaling pathways. The identification of its substrate proteins will further clarify its role in both normal cellular processes and pathological conditions.
Características del producto
category
ELISA Kits
immunogen target
DDB1- and CUL4-associated factor 4 (DCAF4)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
size 1
96 tests
alias
WDR21,WDR21A,WD repeat-containing protein 21A
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
DCAF4
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
Quizá le pueda interesar
DCAF4 Antibody

proveedor
Abbexareference
abx302451Tested Applications
ELISA, WBreactivity
Humanstatus
RUOclonality
PolyclonalDCAF4 Antibody is a Rabbit Polyclonal against DCAF4.
169€ (20 µg)
Ver másDCAF4 Antibody (HRP)

proveedor
Abbexareference
abx310357Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
PolyclonalDCAF4 Antibody (HRP) is a Rabbit Polyclonal against DCAF4 conjugated to HRP.
169€ (20 µg)
Ver másDCAF4 Antibody (FITC)

proveedor
Abbexareference
abx310358reactivity
Humanstatus
RUOclonality
PolyclonalDCAF4 Antibody (FITC) is a Rabbit Polyclonal against DCAF4 conjugated to FITC.
169€ (20 µg)
Ver más