Human DDB1- and CUL4-associated factor 11 (DCAF11) ELISA Kit
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Description
Human DDB1- and CUL4-associated factor 11 (DCAF11) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human DDB1- and CUL4-associated factor 11 (DCAF11) concentrations in serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids.
Documents del producto
Product specifications
| Category | ELISA Kits |
| Immunogen Target | DDB1- and CUL4-associated factor 11 (DCAF11) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Serum, plasma, tissue homogenates, cell culture supernatants and other biological fluids. |
| Availability | Shipped within 5-15 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q8TEB1 |
| OMIM | 613317 |
| Alias | GL014,WDR23,PRO2389,WD repeat-containing protein 23, |
| Background | Elisa kits for DCAF11 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
DDB1 and CUL4 associated factor 11 (DCAF11), also known as WD repeat-containing protein 23 (WDR23), serves as a substrate receptor within the CUL4-DDB1 E3 ubiquitin ligase complex. It contains multiple WD40 repeats that facilitate its role in protein-protein interactions and substrate recognition. DCAF11 is involved in the regulation of various cellular processes, including protein degradation and response to oxidative stress. Studies in model organisms, such as Caenorhabditis elegans, have demonstrated that DCAF11 regulates the nuclear abundance and activity of SKN-1, a transcription factor involved in oxidative stress responses. Additionally, DCAF11 has been implicated in the regulation of microRNA biogenesis and may play a role in modulating the activity of specific transcription factors. Its expression is observed in various tissues, suggesting a broad functional significance. Further research is needed to fully elucidate the range of substrates targeted by DCAF11 and its roles in human health and disease.
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