Human Cytokeratin 19 Fragment (CYFRA-21-1) Protein

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Description
Human Cytokeratin 19 Fragment (CYFRA-21-1) Protein is a purified reagent for cancer research. This protein is produced in MCF-7 cell supernatant.
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Cytokeratin 19 Fragment (CYFRA-21-1) |
| Host | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Origin | Human |
| Conjugation | Unconjugated |
| Purity | <u>Known contaminants:</u> <br> Elecsys CA125 Assay: 875.3 U/ml (1.1%) <br> Elecsys CA15-3 Assay: 6.23 U/ml (< 0.01%) <br> Elecsys CA19-9 Assay: 2.92 U/ml (< 0.01%) |
| Purification | Purified from MCF-7 cell supernatant by ion-exchange chromatography. Product is 0.2 µm filtered. |
| Size 1 | 50 µg |
| Form | Liquid |
| Tested Applications | CLIA |
| Buffer | Phosphate Buffered Saline, pH 7.4 ± 0.1. Does not contain preservatives. |
| Availability | Shipped within 10-20 working days. |
| Storage | Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Background | Protein CYFRA21-1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. Centrifuge before opening to ensure complete recovery of vial contents. Concentration: Specific Protein: 0.077 mg/ml (Cytokeratin 19 Ag) Total Protein: 2362 OD280 Units. |
Descripción
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Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1) Antibody (Capture Ab)
Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1), also known as Keratin, type I cytoskeletal 19, cytokeratin-19 (CK-19) or keratin-19 (K19) is a 40 kDa protein that in humans is encoded by the KRT19 gene. Serum CYFRA 21-1 (cytokeratin-19 fragments) may be a reliable marker of recurrence or therapeutic efficacy, and has been used for monitoring the recurrence of breast cancer and in evaluating therapeutic effects. Serum CYFRA 21-1 has also been used as a biomarker for diagnosis of nonsmall cell lung cancer (NSCLC), and has ben reported to be elevated in nasopharyngeal carcinoma (NPC). It can function as a biomarker for detection and monitoring of NPC.
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Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1) Antibody (Detection Ab)
Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1), also known as Keratin, type I cytoskeletal 19, cytokeratin-19 (CK-19) or keratin-19 (K19) is a 40 kDa protein that in humans is encoded by the KRT19 gene. Serum CYFRA 21-1 (cytokeratin-19 fragments) may be a reliable marker of recurrence or therapeutic efficacy, and has been used for monitoring the recurrence of breast cancer and in evaluating therapeutic effects. Serum CYFRA 21-1 has also been used as a biomarker for diagnosis of nonsmall cell lung cancer (NSCLC), and has ben reported to be elevated in nasopharyngeal carcinoma (NPC). It can function as a biomarker for detection and monitoring of NPC.
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