Human Cytokeratin 19 Fragment (CYFRA-21-1) Protein

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689€ (50 µg)

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935106861
info@markelab.com
name
Human Cytokeratin 19 Fragment (CYFRA-21-1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx060980
tested applications
CLIA

Description

Human Cytokeratin 19 Fragment (CYFRA-21-1) Protein is a purified reagent for cancer research. This protein is produced in MCF-7 cell supernatant.

Documents del producto

Instrucciones
Data sheet
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Product specifications

Category
Proteins and Peptides
Immunogen Target
Cytokeratin 19 Fragment (CYFRA-21-1)
Host
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Origin
Human
Conjugation
Unconjugated
Observed MW
Concentration: Specific Protein: 0.077 mg/ml (Cytokeratin 19 Ag)  Total Protein: 2362 OD280 Units.
Purity
<u>Known contaminants:</u> <br> Elecsys CA125 Assay: 875.3 U/ml (1.1%) <br> Elecsys CA15-3 Assay: 6.23 U/ml (< 0.01%) <br> Elecsys CA19-9 Assay: 2.92 U/ml (< 0.01%)
Purification
Purified from MCF-7 cell supernatant by ion-exchange chromatography. Product is 0.2 µm filtered.
Size 1
50 µg
Form
Liquid
Tested Applications
CLIA
Buffer
Phosphate Buffered Saline, pH 7.4 ± 0.1. Does not contain preservatives.
Availability
Shipped within 10-20 working days.
Storage
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Background
Protein CYFRA21-1
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

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Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1), also known as Keratin, type I cytoskeletal 19, cytokeratin-19 (CK-19) or keratin-19 (K19) is a 40 kDa protein that in humans is encoded by the KRT19 gene. Serum CYFRA 21-1 (cytokeratin-19 fragments) may be a reliable marker of recurrence or therapeutic efficacy, and has been used for monitoring the recurrence of breast cancer and in evaluating therapeutic effects. Serum CYFRA 21-1 has also been used as a biomarker for diagnosis of nonsmall cell lung cancer (NSCLC), and has ben reported to be elevated in nasopharyngeal carcinoma (NPC). It can function as a biomarker for detection and monitoring of NPC.

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Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1) Antibody (Detection Ab)

Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1), also known as Keratin, type I cytoskeletal 19, cytokeratin-19 (CK-19) or keratin-19 (K19) is a 40 kDa protein that in humans is encoded by the KRT19 gene. Serum CYFRA 21-1 (cytokeratin-19 fragments) may be a reliable marker of recurrence or therapeutic efficacy, and has been used for monitoring the recurrence of breast cancer and in evaluating therapeutic effects. Serum CYFRA 21-1 has also been used as a biomarker for diagnosis of nonsmall cell lung cancer (NSCLC), and has ben reported to be elevated in nasopharyngeal carcinoma (NPC). It can function as a biomarker for detection and monitoring of NPC.

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