Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1) Antibody (Capture Ab)
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Description
Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1), also known as Keratin, type I cytoskeletal 19, cytokeratin-19 (CK-19) or keratin-19 (K19) is a 40 kDa protein that in humans is encoded by the KRT19 gene. Serum CYFRA 21-1 (cytokeratin-19 fragments) may be a reliable marker of recurrence or therapeutic efficacy, and has been used for monitoring the recurrence of breast cancer and in evaluating therapeutic effects. Serum CYFRA 21-1 has also been used as a biomarker for diagnosis of nonsmall cell lung cancer (NSCLC), and has ben reported to be elevated in nasopharyngeal carcinoma (NPC). It can function as a biomarker for detection and monitoring of NPC.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Target: Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purity | > 95% (HPLC and SDS-PAGE) |
| Purification | Purified by Protein A or Protein G. |
| Size 1 | 1 mg |
| Form | Liquid |
| Tested Applications | ELISA, WB, CLIA |
| Buffer | 0.01 M PBS (pH 7.4) & 0.15 M NaCl without preservative. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P08727 |
| Gene ID | 3880 |
| OMIM | 148020 |
| Background | Antibody anti-CYFRA21-1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Descripción
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Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1) Antibody (Capture Ab)
Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1), also known as Keratin, type I cytoskeletal 19, cytokeratin-19 (CK-19) or keratin-19 (K19) is a 40 kDa protein that in humans is encoded by the KRT19 gene. Serum CYFRA 21-1 (cytokeratin-19 fragments) may be a reliable marker of recurrence or therapeutic efficacy, and has been used for monitoring the recurrence of breast cancer and in evaluating therapeutic effects. Serum CYFRA 21-1 has also been used as a biomarker for diagnosis of nonsmall cell lung cancer (NSCLC), and has ben reported to be elevated in nasopharyngeal carcinoma (NPC). It can function as a biomarker for detection and monitoring of NPC.
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Cytokeratin 19 Fragment Antigen 21-1 (CYFRA21-1), also known as Keratin, type I cytoskeletal 19, cytokeratin-19 (CK-19) or keratin-19 (K19) is a 40 kDa protein that in humans is encoded by the KRT19 gene. Serum CYFRA 21-1 (cytokeratin-19 fragments) may be a reliable marker of recurrence or therapeutic efficacy, and has been used for monitoring the recurrence of breast cancer and in evaluating therapeutic effects. Serum CYFRA 21-1 has also been used as a biomarker for diagnosis of nonsmall cell lung cancer (NSCLC), and has ben reported to be elevated in nasopharyngeal carcinoma (NPC). It can function as a biomarker for detection and monitoring of NPC.
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