Human CUB Domain Containing Protein 1 (CDCP1) Protein
234€ (10 µg)
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935106861
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name
Human CUB Domain Containing Protein 1 (CDCP1) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166064
tested applications
WB, SDS-PAGE
Description
CUB Domain Containing Protein 1 is a recombinant Human protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | CUB Domain Containing Protein 1 (CDCP1) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 20.1 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Cys689-Glu836 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | Membrane glycoprotein gp140,CD318,TRASK,SIMA135,Subtractive immunization M plus HEp3-associated 135 kDa protein |
| Background | Protein CDCP1 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CDCP1 (CUB Domain Containing Protein 1), also known as CD318 or Trask, is a transmembrane protein widely expressed across cell types, including epithelial cells, stem cells, and notably in certain types of cancer cells. CDCP1 is known for its involvement in various cellular processes, including cell adhesion, migration, and signal transduction. It is a single-pass membrane protein characterized by extracellular CUB domains, which are implicated in protein-protein interactions, especially in cell communication and adhesion mechanisms. CDCP1 plays a crucial role in cancer biology, as its overexpression or aberrant activation has been observed in multiple malignancies, such as lung, colon, and breast cancer, where it contributes to processes like invasion, metastasis, and resistance to apoptosis. This makes CDCP1 an important molecule in cancer progression and a potential target for therapeutic interventions. Moreover, CDCP1 is implicated in non-cancerous biological pathways, including wound healing and tissue remodeling, which involve dynamic changes in cell adhesion and migration.
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