Human COTL1 (Coactosin-like protein) ELISA Kit

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Product specifications
Category | ELISA Kits |
Reactivity | Human |
Detection Method | Colorimetric |
Assay Data | 4 hours |
Assay Type | Sandwich ELISA, Double Antibody |
Test Range | 0.156-10ng/ml |
Sensitivity | 0.094ng/ml |
Size 1 | 96T |
Tested Applications | ELISA |
Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
Availability | Shipped within 10-14 working days. |
Storage | 2-8 °C for 12 months |
UniProt ID | Q14019 |
Alias | Coactosin-like protein, COTL1, CLP |
Background | Elisa kits for COTL1 |
Status | RUO |
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Human COTL1 (Coactosin-like protein) ELISA Kit
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COTL1 antibody
This gene encodes one of the numerous actin-binding proteins which regulate the actin cytoskeleton. This protein binds F-actin, and also interacts with 5-lipoxygenase, which is the first committed enzyme in leukotriene biosynthesis. Although this gene has been reported to map to chromosome 17 in the Smith-Magenis syndrome region, the best alignments for this gene are to chromosome 16. The Smith-Magenis syndrome region is the site of two related pseudogenes.
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COTL1 antibody
Binds to F-actin in a calcium-independent manner. Has no direct effect on actin depolymerization. Acts as a chaperone for ALOX5(5LO), influencing both its stability and activity in leukotrienes synthesis.
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