Human Contactin 4 (CNTN4) ELISA Kit

Este producto es parte de CNTN - contactin
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585€ (96 tests)

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935106861
info@markelab.com
name
Human Contactin 4 (CNTN4) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx252238
tested applications
ELISA

Description

Human Contactin 4 (CNTN4) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Contactin 4 concentrations in serum, plasma, tissue homogenates, cell lysates and other biological fluids.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
ELISA Kits
Immunogen Target
Contactin 4 (CNTN4)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.16 ng/ml - 10 ng/ml
Sensitivity
0.1 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Serum, plasma, tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
Q8IWV2
Alias
AXCAM,BIG-2, Brain-derived immunoglobulin superfamily protein 2,Contactin-4
Background
Elisa Kits for: CNTN4
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Descripción

Contactin 4 (CNTN4), a GPI-anchored member of the immunoglobulin superfamily, is predominantly expressed in the central nervous system, where it regulates neuronal development and synaptic connectivity. CNTN4 is involved in axon guidance, neuronal migration, and synapse formation by mediating homophilic and heterophilic cell-cell interactions. It interacts with other neural cell adhesion molecules and receptors to establish neural circuits during development, particularly in the auditory and visual systems. CNTN4 has been implicated in neurodevelopmental disorders, including autism spectrum disorders (ASD) and attention-deficit hyperactivity disorder (ADHD), where its dysregulation affects neural connectivity and cognitive function. Structural studies reveal that CNTN4 contains extracellular immunoglobulin-like and fibronectin type III domains, which facilitate dynamic interactions essential for its role in neural development. Beyond its role in the nervous system, CNTN4 is also expressed in non-neural tissues, where it may contribute to cell adhesion and signaling in developmental and pathological contexts.

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