Human Contactin 2 (CNTN2) ELISA Kit
611€ (96 tests)
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935106861
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name
Human Contactin 2 (CNTN2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx351767
tested applications
ELISA
Description
Human Contactin 2 (CNTN2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Contactin 2 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Contactin 2 (CNTN2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | 0.19 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q02246 |
| Alias | AXT,TAX,TAX1,EPEO5,FAME5,TAG-1,Transient axonal glycoprotein 1,Axonin-1,Axonal glycoprotein TAG-1,Contactin-2 |
| Background | Elisa kits for CNTN2 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
Contactin 2 (CNTN2), also known as TAG-1 (Transient Axonal Glycoprotein 1), is another GPI-anchored neural adhesion molecule involved in axonal guidance, synaptic development, and neuron-glia interactions. CNTN2 is predominantly expressed during development in the central and peripheral nervous systems, where it plays a critical role in axon fasciculation, neurite outgrowth, and myelination. It interacts with receptors such as L1CAM, Caspr2, and other contactins to promote the formation of functional neural circuits. CNTN2 is also implicated in the organization of nodes of Ranvier, where it stabilizes interactions between axons and myelinating glial cells. Genetic studies have linked CNTN2 mutations to neurodevelopmental and neuropsychiatric disorders, including autism and epilepsy, where its dysregulation disrupts neural connectivity and excitability. It has also been studied in the context of autoimmune diseases like multiple sclerosis, where anti-CNTN2 antibodies contribute to neuroinflammation and demyelination. Structurally, CNTN2 shares immunoglobulin-like and fibronectin type III domains with other contactins, allowing it to mediate dynamic and specific cell-cell interactions in the nervous system.
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