Human Complement Receptor Type 1 / CD35 (CR1) Protein

Name: Human Complement Receptor Type 1 / CD35 (CR1) Protein
Brand: Abbexa
SKU: abx066084
Price: 208 EUR
Availability: OnlineOnly

Este producto es parte de CR1 - complement C3b/C4b receptor 1

Pida mas información

935106861

info@markelab.com

Precio

208€ (10 µg)

Protein CR1

proveedor

Abbexa

reference

abx066084

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human Complement Receptor 1, Erythrocyte (CR1) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).

Background

CR1 (Complement Receptor 1), also known as CD35, is a membrane-bound glycoprotein that plays a key role in the immune system, primarily in mediating the clearance of immune complexes, apoptotic cells, and pathogens through its interaction with components of the complement system. CR1 acts as a receptor for complement proteins C3b and C4b, which are opsonins involved in the activation of the classical and alternative complement pathways. These pathways are critical for enhancing phagocytosis and immune complex clearance, ultimately contributing to host defense against infections. CR1 is expressed on a variety of immune cells, including erythrocytes (red blood cells), leukocytes, monocytes, macrophages, neutrophils, B cells, follicular dendritic cells, and kidney podocytes. The expression pattern of CR1 allows it to fulfill diverse immunological functions, such as regulating complement activation, promoting phagocytosis, and serving as a cofactor for complement cleavage and degradation.

Características del producto

origin

Human

host

E. coli

immunogen target

Complement Receptor Type 1 / CD35 (CR1)

host

E. coli

conjugation

Unconjugated

form

Lyophilized Reconstitute in ddH2O to a concentration up to 0.5 mg/ml. Do not vortex.

tested applications

WB, SDS-PAGE

size 1

10 µg

size 2

50 µg

size 3

100 µg

size 4

200 µg

size 5

500 µg

observerd MW

Molecular Weight: Calculated MW: 30.4 kDa Observed MW (SDS-PAGE): 32 kDa Concentration: Prior to lyophilization: 50 µg/ml Sequence Fragment: Ile1780-Pro2039 Tag: N-terminal His tag

expression

Recombinant

purity

> 95%

buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.

storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.

or code

CR1

dry ice

availability

Shipped within 5-7 working days.

alias

KN,C3BR,C4BR,CD35,Knops blood group,Complement receptor type 1,C3b/C4b receptor

uniprot id

https://www.uniprot.org/uniprotkb/P17927

gene id

https://www.ncbi.nlm.nih.gov/gene/1378

note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.

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proveedor

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reference

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reactivity

human

status

RUO

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