Human Complement Receptor Type 1 / CD35 (CR1) ELISA Kit

546€ (96 tests)
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name
Human Complement Receptor Type 1 / CD35 (CR1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx252271
tested applications
ELISA
Description
Human Complement Receptor Type 1 / CD35 (CR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Complement Receptor Type 1 / CD35 (CR1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Product specifications
Category | ELISA Kits |
Immunogen Target | Complement Receptor Type 1 / CD35 (CR1) |
Reactivity | Human |
Detection Method | Colorimetric |
Assay Data | Quantitative |
Assay Type | Sandwich |
Test Range | 0.156 ng/ml - 10 ng/ml |
Sensitivity | 0.1 ng/ml |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Size 1 | 96 tests |
Size 2 | 5 × 96 tests |
Size 3 | 10 × 96 tests |
Form | Lyophilized |
Tested Applications | ELISA |
Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
Availability | Shipped within 5-7 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
Dry Ice | No |
UniProt ID | P17927 |
OMIM | 120620 |
Alias | KN,C3BR,C4BR,CD35,Knops blood group,Complement receptor type 1,C3b/C4b receptor |
Background | Elisa kits for CR1 |
Status | RUO |
Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CR1 (Complement Receptor 1), also known as CD35, is a membrane-bound glycoprotein that plays a key role in the immune system, primarily in mediating the clearance of immune complexes, apoptotic cells, and pathogens through its interaction with components of the complement system. CR1 acts as a receptor for complement proteins C3b and C4b, which are opsonins involved in the activation of the classical and alternative complement pathways. These pathways are critical for enhancing phagocytosis and immune complex clearance, ultimately contributing to host defense against infections. CR1 is expressed on a variety of immune cells, including erythrocytes (red blood cells), leukocytes, monocytes, macrophages, neutrophils, B cells, follicular dendritic cells, and kidney podocytes. The expression pattern of CR1 allows it to fulfill diverse immunological functions, such as regulating complement activation, promoting phagocytosis, and serving as a cofactor for complement cleavage and degradation.
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