Human Complement Receptor Type 1 / CD35 (CR1) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for CR1
proveedor
Abbexareference
abx151170Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Complement Receptor Type 1 / CD35 (CR1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Complement Receptor Type 1 / CD35 (CR1) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of Complement Receptor 1, Erythrocyte (CR1)
Background
CR1 (Complement Receptor 1), also known as CD35, is a membrane-bound glycoprotein that plays a key role in the immune system, primarily in mediating the clearance of immune complexes, apoptotic cells, and pathogens through its interaction with components of the complement system. CR1 acts as a receptor for complement proteins C3b and C4b, which are opsonins involved in the activation of the classical and alternative complement pathways. These pathways are critical for enhancing phagocytosis and immune complex clearance, ultimately contributing to host defense against infections. CR1 is expressed on a variety of immune cells, including erythrocytes (red blood cells), leukocytes, monocytes, macrophages, neutrophils, B cells, follicular dendritic cells, and kidney podocytes. The expression pattern of CR1 allows it to fulfill diverse immunological functions, such as regulating complement activation, promoting phagocytosis, and serving as a cofactor for complement cleavage and degradation.
Características del producto
category
ELISA Kits
immunogen target
Complement Receptor Type 1 / CD35 (CR1)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.07 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Serum, plasma and other biological fluids.
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
KN,C3BR,C4BR,CD35,Knops blood group,Complement receptor type 1,C3b/C4b receptor
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CR1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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