Human Complement Receptor Type 1 / CD35 (CR1) CLIA Kit
643.5€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Complement Receptor Type 1 / CD35 (CR1) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx196559
tested applications
CLIA
Description
Human Complement Receptor type 1 (CR1) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Complement Receptor type 1 (CR1).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Complement Receptor Type 1 / CD35 (CR1) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 7.81 pg/ml - 500 pg/ml |
| Sensitivity | 4.69 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | KN,C3BR,C4BR,CD35,Knops blood group,Complement receptor type 1,C3b/C4b receptor |
| Background | CLIA Kits CR1 |
| Status | RUO |
| Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
CR1 (Complement Receptor 1), also known as CD35, is a membrane-bound glycoprotein that plays a key role in the immune system, primarily in mediating the clearance of immune complexes, apoptotic cells, and pathogens through its interaction with components of the complement system. CR1 acts as a receptor for complement proteins C3b and C4b, which are opsonins involved in the activation of the classical and alternative complement pathways. These pathways are critical for enhancing phagocytosis and immune complex clearance, ultimately contributing to host defense against infections. CR1 is expressed on a variety of immune cells, including erythrocytes (red blood cells), leukocytes, monocytes, macrophages, neutrophils, B cells, follicular dendritic cells, and kidney podocytes. The expression pattern of CR1 allows it to fulfill diverse immunological functions, such as regulating complement activation, promoting phagocytosis, and serving as a cofactor for complement cleavage and degradation.
Related Products
Human CR1 (Complement Receptor type 1) ELISA Kit
Ver Producto
Human Complement Receptor Type 1 / CD35 (CR1) Protein
Human Complement Receptor 1, Erythrocyte (CR1) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Ver Producto
Complement Receptor Type 1 / CD35 (CR1) Antibody
Polyclonal Antibody to Complement Receptor 1, Erythrocyte (CR1).
Ver Producto