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Human Complement Receptor 2 / CD21 (CR2) ELISA Kit
Pida mas información
935106861
info@markelab.com
Precio
618.75€ (96 tests)
Elisa Kits CR2
proveedor
Abbexareference
abx151143Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Complement Receptor 2 / CD21 (CR2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Complement Receptor 2 / CD21 (CR2) concentrations in serum, plasma and other biological fluids. This assay has high sensitivity and excellent specificity for detection of CR2No significant cross-reactivity or interference between CR2 and analogues was observed.
Background
CR2, also known as complement receptor type 2 (CR2) or CD21, is a crucial protein involved in the immune response, particularly in the regulation and activation of B cells and the complement system. It serves as a receptor for fragments of complement component C3, specifically C3d, C3dg, and iC3b, which are breakdown products of C3b, an integral part of the complement system. By binding these complement fragments, CR2 plays a key role in amplifying the immune response and facilitating interactions between the innate and adaptive arms of the immune system. CR2 is predominantly expressed on the surface of B lymphocytes, follicular dendritic cells, and some epithelial cells. Its most well-known function is to enhance B-cell activation by linking the complement system to the B-cell receptor (BCR) signaling pathway. This enhances B-cell sensitivity to antigens, especially during the formation of immunological memory.
Características del producto
category
ELISA Kits
immunogen target
Complement Receptor 2 / CD21 (CR2)
reactivity
Human
test range
78 pg/ml - 5000 pg/ml
sensitivity
< 31 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Serum,Plasma,Other biological fluids
size 1
96 tests
size 2
5 × 96 tests
size 3
10 × 96 tests
alias
CR,C3DR,CD21,CVID7,SLEB9,Complement receptor type 2,Complement C3d receptor,Epstein-Barr virus receptor,EBV receptor
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
CR2
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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