Human Colony Stimulating Factor 2 Receptor Beta (CSF2RB) ELISA Kit

Este producto es parte de CSF2RB - colony stimulating factor 2 receptor subunit beta
Human Colony Stimulating Factor 2 Receptor Beta (CSF2RB) ELISA Kit
585€ (96 tests)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
Human Colony Stimulating Factor 2 Receptor Beta (CSF2RB) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx252280
Tested Applications
ELISA

Description

Human Colony Stimulating Factor 2 Receptor Beta (CSF2RB) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Colony Stimulating Factor 2 Receptor Beta (CSF2RB) concentrations in tissue homogenates, cell lysates and other biological fluids.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
ELISA Kits
Immunogen Target
Colony Stimulating Factor 2 Receptor Beta (CSF2RB)
Reactivity
Human
Detection Method
Colorimetric
Assay Data
Quantitative
Assay Type
Sandwich
Test Range
0.156 ng/ml - 10 ng/ml
Sensitivity
0.1 ng/ml
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Size 1
96 tests
Size 2
5 × 96 tests
Size 3
10 × 96 tests
Form
Standard Form: Lyophilized
Tested Applications
ELISA
Sample Type
Tissue homogenates, cell lysates and other biological fluids.
Availability
Shipped within 5-7 working days.
Storage
Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
Dry Ice
No
UniProt ID
P32927
Alias
Cytokine receptor common subunit beta,CD131,IL3RB,IL5RB,SMDP5,CDw131,betaGMR,GM-CSF/IL-3/IL-5 receptor common beta subunit
Background
Elisa Kits for: CSF2RB
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout.

Background

The Colony Stimulating Factor 2 Receptor Subunit Beta (CSF2RB), also known as common beta chain (βc), is an integral part of the receptor complex for several cytokines, notably granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin-3 (IL-3), and interleukin-5 (IL-5). These cytokines play essential roles in hematopoiesis, the immune system, and inflammatory processes by driving the proliferation, differentiation, and activation of various hematopoietic cells. CSF2RB is thus crucial for normal immune function and has also been implicated in inflammatory responses, tissue repair, and pathological conditions such as chronic inflammation and certain cancers. Unlike its alpha counterparts (CSF2RA, IL3RA, and IL5RA), which are cytokine-specific, CSF2RB serves as a shared receptor subunit in these cytokine receptor complexes. This shared receptor structure allows it to transmit signals from multiple cytokines, although it does not bind cytokines directly. Instead, CSF2RB’s main function is to initiate downstream signaling cascades once the cytokine and alpha subunit have bound, forming a functional receptor complex. This receptor complex predominantly activates the JAK/STAT and MAPK signaling pathways, with substantial impact on immune responses, hematopoiesis, and cellular responses to stress.

Productos relacionados

abx031871

CSF2RB (pY766) Antibody

CSF2RB (also known as CSF2RB) is a common beta chain of the high affinity receptor for IL-3, IL-5 and GM-CSF. Defective …

Ver producto
abx032814

Colony Stimulating Factor 2 Receptor Beta (CSF2RB) Antibody

Purified rabbit polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is first purified by pr…

Ver producto
abx066031

Human Colony Stimulating Factor 2 Receptor Beta (CSF2Rb) Protein

Human Colony Stimulating Factor 2 Receptor Beta (CSF2Rb) is a recombinant Human protein expressed in E. coli.…

Ver producto