Human Cluster of Differentiation 81 (CD81) Protein

Este producto es parte de CD81 - CD81 molecule
Human Cluster of Differentiation 81 (CD81) Protein

Pida mas información

935106861

info@markelab.com

Precio

247€ (10 µg)

Protein CD81

proveedor

Abbexa

reference

abx168684

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human CD81 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).


Background

CD81, also known as TAPA-1 (Target of the Anti-Proliferative Antibody 1), is a member of the tetraspanin family, a group of proteins that are widely expressed across various tissues and cell types. Tetraspanins are integral membrane proteins involved in a variety of biological processes, including cell adhesion, migration, proliferation, and signal transduction. CD81 has a well-established role in immune cell function, particularly in the regulation of B and T cell activity, as well as in viral infections. Most notably, CD81 is a critical component in the entry process of hepatitis C virus (HCV) into host cells. The CD81 gene is located on chromosome 11p15.5 and encodes a protein that is involved in the formation of tetraspanin-enriched microdomains. These microdomains facilitate the assembly of various signaling complexes at the cell membrane, influencing the function of associated proteins. CD81 is widely expressed on multiple cell types, including lymphocytes, hepatocytes, epithelial cells, and fibroblasts

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Cluster of Differentiation 81 (CD81)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 13.4 kDa Observed MW (SDS-PAGE): 13 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Phe113-Lys201 Tag: N-terminal His tag


expression

Recombinant


purity

> 97%


buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

CD81


dry ice

No


availability

Shipped within 5-7 working days.


alias

CVID6,S5.7,CD81 antigen,26 kDa cell surface protein TAPA-1,Target of the antiproliferative antibody 1,Tetraspanin-28,Tspan-28,


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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