Human Cluster of Differentiation 276 (CD276) Protein
767€ (50 µg)
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name
Human Cluster of Differentiation 276 (CD276) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx651310
tested applications
WB, SDS-PAGE
Description
Cluster Of Differentiation 276 (CD276) Protein (Active) is an active protein from Human.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Cluster of Differentiation 276 (CD276) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 22.4 kDa Observed MW: 22 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Thr47-Ser219 Tag: N-terminal His tag |
| Purity | > 97% |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 500 µg |
| Size 5 | 1 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q5ZPR3 |
| Alias | B7H3,B7-H3,B7RP-2,4Ig-B7-H3,B7 homolog 3,Costimulatory molecule |
| Background | Protein CD276 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD276, also known as B7-H3, is a protein encoded by the CD276 gene located on chromosome 15q24.1. It is a member of the B7 family of immune regulatory molecules, which are known to play crucial roles in the modulation of immune responses. B7-H3 was first identified in 2001 and has since been recognized for its involvement in immune regulation, particularly in the context of cancer, autoimmunity, and transplantation. The expression of B7-H3 is widespread, found on various cell types, including dendritic cells, monocytes, activated T cells, and several non-immune cells such as fibroblasts, endothelial cells, and certain epithelial cells. Its expression can be induced by inflammatory cytokines and other immune signals.
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