Human Cluster of Differentiation 276 (CD276) CLIA Kit

Human Cluster Of Differentiation 276 (CD276) CLIA Kit es un kit CLIA tipo Sandwich para su uso con suero, plasma, homogeneizados de tejidos, lisados celulares y otros fluidos biológicos.

Background

CD276, also known as B7-H3, is a protein encoded by the CD276 gene located on chromosome 15q24.1. It is a member of the B7 family of immune regulatory molecules, which are known to play crucial roles in the modulation of immune responses. B7-H3 was first identified in 2001 and has since been recognized for its involvement in immune regulation, particularly in the context of cancer, autoimmunity, and transplantation. The expression of B7-H3 is widespread, found on various cell types, including dendritic cells, monocytes, activated T cells, and several non-immune cells such as fibroblasts, endothelial cells, and certain epithelial cells. Its expression can be induced by inflammatory cytokines and other immune signals.