Human Cluster of Differentiation 24 (CD24) Protein
208€ (10 µg)
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name
Human Cluster of Differentiation 24 (CD24) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065919
tested applications
WB, SDS-PAGE
Description
Recombinant Cluster Of Differentiation 24 (CD24) is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Cluster of Differentiation 24 (CD24) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 35.3 kDa Observed MW (SDS-PAGE): 35 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ser27-Ser80 Tag: N-terminal His tag and GST tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P25063 |
| Alias | CD24A,Signal transducer CD24,Small cell lung carcinoma cluster 4 antigen |
| Background | Protein CD24 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD24 is a small, heavily glycosylated cell surface protein that plays a crucial role in modulating immune responses, cell adhesion, and signal transduction. It is expressed in a wide range of tissues, including hematopoietic cells, neurons, epithelial cells, and cancer cells. CD24 has gained significant attention for its role in the immune system and its involvement in cancer biology. It has been implicated in both autoimmune diseases and tumor progression, making it an important molecule for understanding various pathophysiological processes. CD24 is involved in modulating immune responses, particularly in the context of inflammation, tumor immunology, and autoimmunity. It acts as a key regulator of innate immunity by interacting with various receptors, such as Siglec-10 on macrophages, to dampen inflammatory responses and promote immune tolerance. In the tumor microenvironment, CD24 can contribute to the immune evasion of cancer cells, allowing them to escape destruction by the immune system.
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