Human Keratin 18 (KRT18) Protein

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Description
Recombinant full length human Cytokeratin 18 protein with molecular weight 47.3 kDa.
Documents del producto
Product specifications
| Category | Proteins and Peptides  | 
| Immunogen Target | Keratin 18 (KRT18)  | 
| Host | E. coli  | 
| Origin | Human  | 
| Conjugation | Unconjugated  | 
| Observed MW | Molecular Weight: 47.3 kDa Concentration: 1.6 mg/ml Sequence Fragment: Full length Human CK18 Protein.  | 
| Expression | Recombinant  | 
| Purity | > 95% (SDS-PAGE)  | 
| Size 1 | 100 µg  | 
| Size 2 | 1 mg  | 
| Form | Liquid  | 
| Tested Applications | ELISA, SDS-PAGE  | 
| Buffer | Tris-HCl (pH 7.4 ± 0.2) with 0.2% sodium azide.  | 
| Availability | Shipped within 5-10 working days.  | 
| Storage | Aliquot and store at -20°C or -80°C for long term. Avoid repeated freeze/thaw cycles.  | 
| Dry Ice | No  | 
| UniProt ID | P05783  | 
| Gene ID | 3875  | 
| OMIM | 148070  | 
| Background | Protein KRT18  | 
| Status | RUO  | 
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.  | 
Descripción
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Keratins are a large family of proteins that form the intermediate filament cytoskeleton of epithelial cells, which are classified into two major sequence types. Type I keratins are a group of acidic intermediate filament proteins, including K9–K23, and the hair keratins Ha1–Ha8. Type II keratins are the basic or neutral courterparts to the acidic type I keratins, including K1–K8, and the hair keratins, Hb1–Hb6. KRT18, also named as CYK18, PIG46 and K18, is the most commonly found members of the intermediate filament gene family. KRT18 is a type I keratin which is found primarily in non squamous epithelia and is present in a majority of adenocarcinomas and ductal carcinomas but not in squamous cell carcinomas.
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