Human CHRM3 (Muscarinic acetylcholine receptor M3) ELISA Kit
Contáctenos para saber el precio
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Human CHRM3 (Muscarinic acetylcholine receptor M3) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH1956
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.313-20ng/ml |
| Sensitivity | 0.188ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | P20309 |
| Alias | CHRM3,Chrm-3,M3R,cholinergic receptor, muscarinic 3,cholinergic receptor,cholinergic receptor, muscarinic 3, cardiac,M3 receptor,HM3, PBS, EGBRS, m3AChR |
| Background | Elisa kits for CHRM3 |
| Status | RUO |
Background
CHRM3 encodes the cholinergic receptor muscarinic 3, another receptor in the muscarinic acetylcholine receptor family that primarily couples to Gq/11 proteins. Upon activation by acetylcholine, CHRM3 stimulates phospholipase C (PLC), leading to increased production of inositol triphosphate (IP3) and diacylglycerol (DAG), which together elevate intracellular calcium ion concentrations and activate downstream signaling pathways. CHRM3 is abundantly expressed in smooth muscle tissues of the gastrointestinal tract, bladder, and lungs, where it plays a key role in mediating smooth muscle contraction. It is critical for processes such as gastrointestinal motility, bronchoconstriction, and urinary bladder contraction. In the CNS, CHRM3 contributes to cognitive function and neuronal signaling. Dysregulation of CHRM3 has been implicated in disorders like overactive bladder syndrome, asthma, and certain types of cancer. Pharmacologically, CHRM3 antagonists, such as antimuscarinics, are used to treat conditions like overactive bladder, while agonists could be explored for potential use in cognitive enhancement. CHRM3 remains a critical target for both autonomic regulation and emerging therapies in neurological disorders and cancer research.
Productos relacionados
Muscarinic Acetylcholine Receptor M3 (CHRM3) Antibody
CHRM3 Antibody is a Rabbit Polyclonal Antibody against CHRM3.…
Ver producto
Mouse Muscarinic acetylcholine receptor M3 (CHRM3) ELISA Kit
Mouse Muscarinic acetylcholine receptor M3 (CHRM3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement o…
Ver producto
Human Muscarinic acetylcholine receptor M3 (CHRM3) ELISA Kit
Human Muscarinic acetylcholine receptor M3 (CHRM3) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement o…
Ver producto