Human CD302 antigen (CD302) ELISA Kit

Background

CD302, also known as the CD302 molecule or CLEC13A, is a protein within the C-type lectin receptor (CLR) family and plays a role in the immune system. Expressed predominantly on dendritic cells, monocytes, macrophages, and granulocytes, CD302 is a transmembrane receptor that is thought to facilitate immune cell migration, adhesion, and pathogen recognition. Structurally, CD302 shares characteristics with other C-type lectins, specifically with a C-type lectin-like domain (CTLD) that mediates interactions with carbohydrates on microbial surfaces. As a receptor, CD302 is involved in various processes including endocytosis and phagocytosis, making it an essential component of immune cell function and pathogen defense mechanisms. CD302’s expression across various immune cell types suggests it plays a broad role in both innate and adaptive immune responses, particularly in antigen-presenting cells (APCs) like macrophages and dendritic cells. Given its cell-surface localization and involvement in binding to carbohydrate structures, CD302 is of significant interest in studies related to host-pathogen interactions, immune surveillance, and potentially in autoimmune and inflammatory diseases.