Human CD276 Antigen (CD276) Protein

Este producto es parte de CD276 molecule
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312€ (20 µg)

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935106861
info@markelab.com
name
Human CD276 Antigen (CD276) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx694101
tested applications
SDS-PAGE

Description

Human CD276 Antigen (CD276) Protein is a recombinant Human protein expressed in HEK293 cells.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Host
HEK293 cells
Origin
Human
Observed MW
Molecular Weight: Calculated MW: 47.3 kDa  Observed MW (SDS-PAGE): 60-80 kDa
Sequence Fragment: Leu29-Thr461
Tag: C-terminal His tag
Expression
Recombinant
Purity
>95% (SDS-PAGE)
Size 1
20 µg
Size 2
100 µg
Form
Lyophilized Reconstitute in sterile H2O. Do not vortex.
Tested Applications
SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 5% - 8% Trehalose, Mannitol and 0.01% Tween-80.
Availability
Shipped within 5-15 working days.
Storage
Store lyophilized between -20 °C and -80 °C.
Dry Ice
No
UniProt ID
Q5ZPR3
Alias
B7H3,B7-H3,B7RP-2,4Ig-B7-H3,B7 homolog 3,Costimulatory molecule
Background
Protein CD276
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

CD276, also known as B7-H3, is a protein encoded by the CD276 gene located on chromosome 15q24.1. It is a member of the B7 family of immune regulatory molecules, which are known to play crucial roles in the modulation of immune responses. B7-H3 was first identified in 2001 and has since been recognized for its involvement in immune regulation, particularly in the context of cancer, autoimmunity, and transplantation. The expression of B7-H3 is widespread, found on various cell types, including dendritic cells, monocytes, activated T cells, and several non-immune cells such as fibroblasts, endothelial cells, and certain epithelial cells. Its expression can be induced by inflammatory cytokines and other immune signals.

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