Human CD21 (Complement Receptor 2) ELISA Kit

Este producto es parte de CR2 - complement C3d receptor 2
Human CD21 (Complement Receptor 2) ELISA Kit
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Name
Human CD21 (Complement Receptor 2) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH0078
Tested Applications
ELISA

Documentos del producto

Instrucciones
Descargar
Data sheet

Especificaciones del producto

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.313-20ng/ml
Sensitivity
0.188ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
O15181
Alias
CR,C3DR,CD21,CVID7,SLEB9,Complement receptor type 2,Complement C3d receptor,Epstein-Barr virus receptor,EBV receptor
Background
Elisa kits for CR2
Status
RUO

Background

CR2, also known as complement receptor type 2 (CR2) or CD21, is a crucial protein involved in the immune response, particularly in the regulation and activation of B cells and the complement system. It serves as a receptor for fragments of complement component C3, specifically C3d, C3dg, and iC3b, which are breakdown products of C3b, an integral part of the complement system. By binding these complement fragments, CR2 plays a key role in amplifying the immune response and facilitating interactions between the innate and adaptive arms of the immune system. CR2 is predominantly expressed on the surface of B lymphocytes, follicular dendritic cells, and some epithelial cells. Its most well-known function is to enhance B-cell activation by linking the complement system to the B-cell receptor (BCR) signaling pathway. This enhances B-cell sensitivity to antigens, especially during the formation of immunological memory.

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