Human CD109 (CD109 antigen) ELISA Kit
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Name
Human CD109 (CD109 antigen) ELISA Kit
Category
ELISA Kits
Provider
FineTest
Reference
EH1701
Tested Applications
ELISA
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | 4 hours |
| Assay Type | Sandwich ELISA, Double Antibody |
| Test Range | 0.313-20ng/ml |
| Sensitivity | 0.188ng/ml |
| Size 1 | 96T |
| Tested Applications | ELISA |
| Sample Type | Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples |
| Availability | Shipped within 10-14 working days. |
| Storage | 2-8 °C for 12 months |
| UniProt ID | Q6YHK3 |
| Alias | p180,r150,CPAMD7,Platelet-specific Gov antigen,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 7 |
| Background | Elisa kits for CD109 |
| Status | RUO |
Background
CD109 molecule is a glycosylphosphatidylinositol (GPI)-anchored cell surface protein that plays a role in regulating various cellular processes, including immune response and hematopoiesis CD109 is expressed on a variety of cells, including T-cells, endothelial cells, and platelets, and functions as a negative regulator of the transforming growth factor-beta (TGF-β) signaling pathway, which is critical for cell proliferation, differentiation, and immune response modulation By interacting with TGF-β receptors, CD109 modulates TGF-β signaling, potentially inhibiting excessive fibrosis or immune suppression Dysregulation of CD109 expression has been linked to certain cancers, where it can enhance tumor cell survival by suppressing anti-tumor immune responses It is also associated with autoimmune diseases, where its role in immune modulation can influence the development of inflammatory conditions Recent studies have explored CD109 as a potential biomarker for various diseases, including cancer and autoimmune disorders, emphasizing its importance in cellular regulation and immune homeostasis
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