Human Caspase Recruitment Domain Family, Member 9 (CARD9) Protein

Este producto es parte de CARD - Caspase recruitment domain-containing protein
Human Caspase Recruitment Domain Family, Member 9 (CARD9) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein CARD9

proveedor

Abbexa

reference

abx166700

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Caspase Recruitment Domain Family, Member 9 Protein is a recombinant Human protein expressed in E. coli.


Background

CARD9 is a key protein in the immune response, particularly in the signaling pathways of innate immunity. It is involved in activating the NF-κB signaling pathway, which plays a crucial role in inflammation and immune cell activation. CARD9 acts as an adaptor protein that connects pattern recognition receptors, such as C-type lectin receptors (CLRs), to downstream signaling pathways. This enables the recognition of microbial pathogens and triggers an immune response. Specifically, CARD9 is important in the recognition of fungal and bacterial infections, where it contributes to the activation of inflammatory cytokines and the recruitment of immune cells. Mutations or deficiencies in CARD9 can lead to immune system dysfunctions, including increased susceptibility to fungal infections and certain autoimmune diseases. CARD9 has therefore emerged as a critical target for understanding and potentially treating immune-related disorders and infections.

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Caspase Recruitment Domain Family, Member 9 (CARD9)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 33.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Asp26-Leu283 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

CARD9


dry ice

No


availability

Shipped within 5-7 working days.


alias

CARD9, CANDF2,Hcard9,IMD103


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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