Human C-Type Lectin Domain Family 12 Member A (CLEC12A) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for CLEC12A
proveedor
Abbexareference
abx384743Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human C-Type Lectin Domain Family 12 Member A (CLEC12A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human CLEC12A concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CLEC12A (C-type lectin domain family 12 member A) is a member of the C-type lectin receptor (CLR) family, a group of proteins characterized by their ability to recognize carbohydrate structures on the surface of pathogens or host cells. As a receptor with immunoregulatory functions, CLEC12A plays a critical role in the immune system, particularly in the context of myeloid cell biology. Its primary expression is found on a variety of immune cells, especially those within the myeloid lineage, including monocytes, macrophages, and dendritic cells. CLEC12A is involved in modulating immune responses to pathogens and tumors, playing a role in both the innate immune system and in the cross-talk between innate and adaptive immunity.CLEC12A has garnered attention due to its involvement in inflammation and its potential therapeutic implications in diseases involving immune dysregulation, such as cancer and autoimmune disorders. Understanding its functions, structure, and signaling pathways is critical for determining its role in immune responses and for developing therapeutic strategies to target CLEC12A in various clinical contexts.
Características del producto
category
ELISA Kits
immunogen target
C-Type Lectin Domain Family 12 Member A (CLEC12A)
reactivity
Human
test range
0.156 ng/ml - 10 ng/ml
sensitivity
< 0.094 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
CLL1,MICL,CD371,CLL-1,DCAL-2,C-type lectin-like molecule 1,Myeloid inhibitory C-type lectin-like receptor,Dendritic cell-associated lectin 2
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CLEC12A
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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