Human C-Type Lectin Domain Family 10 Member A / CD301 (CLEC10A) Protein
234€ (2 µg)
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935106861
info@markelab.com
name
Human C-Type Lectin Domain Family 10 Member A / CD301 (CLEC10A) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680129
tested applications
SDS-PAGE
Description
Human C-Type Lectin Domain Family 10 Member A / CD301 (CLEC10A) Protein is a recombinant protein produced in Sf9, Insect cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | C-Type Lectin Domain Family 10 Member A / CD301 (CLEC10A) |
| Host | Insect |
| Origin | Human |
| Conjugation | Unconjugated |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 2 µg |
| Size 2 | 10 µg |
| Size 3 | 1 mg |
| Form | Liquid |
| Tested Applications | SDS-PAGE |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| Alias | C-type lectin domain family 10 member A,HML,MGL,HML2,CD301,CLECSF13,CLECSF14,C-type lectin superfamily member 14,Macrophage lectin 2 |
| Background | Protein CLEC10A |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CLEC10A (C-type lectin domain containing 10A), also known as CD301 or MGL (Macrophage Galactose-Type Lectin), is a transmembrane protein in the C-type lectin receptor (CLR) family primarily expressed on antigen-presenting cells such as dendritic cells, macrophages, and certain monocytes. CLEC10A is part of the innate immune system, specializing in recognizing carbohydrate structures on the surfaces of cells and pathogens. Specifically, it binds to terminal galactose and N-acetylgalactosamine (GalNAc) residues, making it essential for identifying certain pathogens and interacting with glycoproteins on cellular surfaces. CLEC10A’s specificity for galactose-containing glycans allows it to function in immune surveillance, pathogen clearance, and immunomodulation, making it a focal point in immune-related research. Its expression on dendritic cells and macrophages positions it to play a key role in the innate immune system's interactions with the adaptive immune response, particularly in tissue immune environments. CLEC10A’s involvement in recognizing glycosylated antigens has implications for disease processes, including infections, cancer, and autoimmune conditions.
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