Human C-Type Lectin Domain Family 10 Member A / CD301 (CLEC10A) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for CLEC10A
proveedor
Abbexareference
abx259489Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human C-Type Lectin Domain Family 10 Member A / CD301 (CLEC10A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human C-Type Lectin Domain Family 10 Member A / CD301 (CLEC10A) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
CLEC10A (C-type lectin domain containing 10A), also known as CD301 or MGL (Macrophage Galactose-Type Lectin), is a transmembrane protein in the C-type lectin receptor (CLR) family primarily expressed on antigen-presenting cells such as dendritic cells, macrophages, and certain monocytes. CLEC10A is part of the innate immune system, specializing in recognizing carbohydrate structures on the surfaces of cells and pathogens. Specifically, it binds to terminal galactose and N-acetylgalactosamine (GalNAc) residues, making it essential for identifying certain pathogens and interacting with glycoproteins on cellular surfaces. CLEC10A’s specificity for galactose-containing glycans allows it to function in immune surveillance, pathogen clearance, and immunomodulation, making it a focal point in immune-related research. Its expression on dendritic cells and macrophages positions it to play a key role in the innate immune system's interactions with the adaptive immune response, particularly in tissue immune environments. CLEC10A’s involvement in recognizing glycosylated antigens has implications for disease processes, including infections, cancer, and autoimmune conditions.
Características del producto
category
ELISA Kits
immunogen target
C-Type Lectin Domain Family 10 Member A / CD301 (CLEC10A)
reactivity
Human
test range
0.313 ng/ml - 20 ng/ml
sensitivity
< 0.188 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
C-type lectin domain family 10 member A,HML,MGL,HML2,CD301,CLECSF13,CLECSF14,C-type lectin superfamily member 14,Macrophage lectin 2
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
CLEC10A
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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