Human C-myc promoter-binding protein (DENND4A) ELISA Kit

Product specifications

ELISA Kits

C-myc promoter-binding protein (DENND4A)

Human

Colorimetric

Quantitative

0.156 ng/ml - 10 ng/ml

Optimal dilutions/concentrations should be determined by the end user.

96 tests

Lyophilized

ELISA

Tissue homogenates, cell lysates and other biological fluids.

Shipped within 5-15 working days. The validity for this kit is 6 months.

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.

No

Q7Z401

600382

IRLB,MYCPBP,C-myc promoter-binding protein

Elisa kits for DENND4A

RUO

Validity: The validity for this kit is 6 months.
This product is for research use only.   The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments.   Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.

Descripción

DENN domain containing 4A (DENND4A) is a guanine nucleotide exchange factor (GEF) that plays a key role in activating Rab GTPases, specifically Rab10, which is central to vesicle trafficking, membrane remodeling, and exocytosis. DENND4A facilitates the GDP-to-GTP exchange on Rab10, enabling its active role in directing vesicles to the plasma membrane or specific intracellular compartments. Its regulatory functions are critical for receptor recycling, protein secretion, and cellular signaling pathways. DENND4A is expressed ubiquitously but exhibits higher expression in tissues with heightened vesicular transport demands, such as epithelial cells, neurons, and endocrine tissues. It also plays a significant role in maintaining endocytic recycling and cellular polarization, processes that ensure proper distribution of proteins and lipids within cells. Dysregulation of DENND4A has been linked to defects in membrane trafficking and signaling, contributing to conditions such as cancer, metabolic syndromes, and neurodegenerative disorders. Its involvement in intracellular transport pathways underscores its essential role in maintaining cellular homeostasis and adaptive cellular responses.

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Human C-myc promoter-binding protein (DENND4A) ELISA Kit

Human C-myc promoter-binding protein (DENND4A) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human C-myc promoter-binding protein (DENND4A) concentrations in tissue homogenates, cell lysates and other biological fluids.

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