Human Beta adducin (ADD2) ELISA Kit
715€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human Beta adducin (ADD2) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx259433
tested applications
ELISA
Description
Human Beta adducin (ADD2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Adducin 2 (ADD2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Beta adducin (ADD2) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.19 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | P35612 |
| Gene ID | 119 |
| OMIM | 102681 |
| Alias | ADDB,ADDUCIN 2 |
| Background | Elisa kits for ADD2 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ADD2 encodes beta-adducin, a component of the adducin protein family that works synergistically with alpha-adducin to regulate actin-spectrin interactions in the cytoskeleton. It is expressed predominantly in erythrocytes and the brain, where it contributes to maintaining the structural integrity of cell membranes and regulating intracellular signaling pathways. In erythrocytes, beta-adducin enhances membrane stability by crosslinking spectrin and actin filaments, ensuring the proper mechanical properties of red blood cells. Beta-adducin has also been implicated in neuronal development, particularly in synapse formation and function. Dysregulation or mutations in ADD2 are linked to neurological disorders, including cognitive impairments, and may exacerbate structural defects in red blood cells, contributing to anemia or other hematological abnormalities.
Related Products
ADD2 antibody
Ver Producto
Adducin 2 (ADD2) Antibody
Adducin 2 (Beta) Antibody is a Rabbit Polyclonal antibody against Adducin 2 (Beta).
Ver Producto