Human Beta adducin (ADD2) ELISA Kit

Este producto es parte de ADD - Adducin ( Alpha,Beta,Gamma)
Human Beta adducin (ADD2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ADD2

proveedor

Abbexa

reference

abx259433

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Beta adducin (ADD2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Adducin 2 (ADD2) concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

ADD2 encodes beta-adducin, a component of the adducin protein family that works synergistically with alpha-adducin to regulate actin-spectrin interactions in the cytoskeleton. It is expressed predominantly in erythrocytes and the brain, where it contributes to maintaining the structural integrity of cell membranes and regulating intracellular signaling pathways. In erythrocytes, beta-adducin enhances membrane stability by crosslinking spectrin and actin filaments, ensuring the proper mechanical properties of red blood cells. Beta-adducin has also been implicated in neuronal development, particularly in synapse formation and function. Dysregulation or mutations in ADD2 are linked to neurological disorders, including cognitive impairments, and may exacerbate structural defects in red blood cells, contributing to anemia or other hematological abnormalities.

Características del producto

category

ELISA Kits


immunogen target

Beta adducin (ADD2)


reactivity

Human


test range

0.313 ng/ml - 20 ng/ml


sensitivity

< 0.19 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


size 2

5 × 96 tests


size 3

10 × 96 tests


alias

ADDB,ADDUCIN 2


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ADD2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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