Human Beta-2 Adrenergic Receptor (ADRB2) ELISA Kit

Este producto es parte de ADRB - Adrenergic receptor Beta
Human Beta-2 Adrenergic Receptor (ADRB2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

687.5€ (96 tests)

Elisa Kits ADRB2

proveedor

Abbexa

reference

abx576662

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Beta-2 Adrenergic Receptor (ADRB2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Beta-2 adrenergic receptor concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

The adrenergic receptor beta-2 (ADRB2) is another G-protein-coupled receptor widely distributed in smooth muscle tissues, including the lungs, blood vessels, and uterus. ADRB2 activation by catecholamines induces smooth muscle relaxation through cAMP-mediated pathways, leading to bronchodilation, vasodilation, and uterine relaxation. In the respiratory system, ADRB2 is critical for airway relaxation, making it a primary target for bronchodilators used in asthma and chronic obstructive pulmonary disease (COPD) management. Additionally, ADRB2 plays a role in glycogenolysis in the liver and skeletal muscles, promoting energy mobilization during stress or exercise. Genetic variants in ADRB2, such as Gly16Arg and Gln27Glu, influence receptor sensitivity and have been associated with differential responses to beta-agonists and susceptibility to asthma. Overactivation of ADRB2 can lead to desensitization, reducing therapeutic efficacy over time. Its involvement in multiple physiological processes underscores ADRB2's importance in both metabolic and respiratory regulation.

Características del producto

category

ELISA Kits


immunogen target

Beta-2 Adrenergic Receptor (ADRB2)


reactivity

Human


test range

0.156 ng/ml - 10 ng/ml


assay type

Sandwich


assay data

Quantitative


detection method

Colorimetric


sample type

Tissue homogenates,Cell lysates,Other biological fluids


size 1

96 tests


alias

ADRB2,ADRB2R,ADRBR,B2AR,Adrb-2,beta 2-AR,Gpcr7,BAR,ARB2


storage

Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit


or code

ADRB2


dry ice

No


note

This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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