Human Bcl2L2 (Bcl-2 Like Protein 2) ELISA Kit

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935106861
info@markelab.com
name
Human Bcl2L2 (Bcl-2 Like Protein 2) ELISA Kit
category
ELISA Kits
provider
FineTest
reference
EH4222
tested applications
ELISA

Documents del producto

Instrucciones
Descargar
Data sheet

Product specifications

Category
ELISA Kits
Reactivity
Human
Detection Method
Colorimetric
Assay Data
4 hours
Assay Type
Sandwich ELISA, Double Antibody
Test Range
0.313-20ng/ml
Sensitivity
0.188ng/ml
Size 1
96T
Tested Applications
ELISA
Sample Type
Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples
Availability
Shipped within 10-14 working days.
Storage
2-8 °C for 12 months
UniProt ID
Q9HB09
Alias
BPR,Bcl-2-related proline-rich protein
Background
Elisa kits for Bcl2L12
Status
RUO

BCL2 like 12 (BCL2L12) is a member of the Bcl-2 protein family, which regulates apoptosis by controlling mitochondrial outer membrane permeabilization BCL2L12 functions as an anti-apoptotic protein, inhibiting the pro-apoptotic signals that trigger programmed cell death It shares structural similarities with other Bcl-2 family members, especially in the BH domains that mediate protein interactions BCL2L12’s primary function is to protect cells from apoptotic stimuli, thus contributing to cellular survival in response to stress or injury However, its dysregulation can be problematic, as its overexpression has been linked to cancer, where it supports the survival of tumor cells and prevents apoptosis, allowing for uncontrolled cell proliferation Additionally, BCL2L12 is thought to play a role in regulating immune cell responses and influencing the survival of certain immune cells during inflammatory conditions Studies also suggest that it may impact synaptic plasticity in the brain, making it relevant for neurodegenerative diseases where cell death is a major factor

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