Human Bcl2-related protein A1 (BCL2A1) ELISA Kit
611€ (96 tests)
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Name
Human Bcl2-related protein A1 (BCL2A1) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx352338
Tested Applications
ELISA
Description
Human Bcl2-related protein A1 (BCL2A1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Bcl-2-related protein A1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | Bcl2-related protein A1 (BCL2A1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 31.3 pg/ml - 2000 pg/ml |
| Sensitivity | 18.8 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q16548 |
| Gene ID | 597 |
| OMIM | 601056 |
| Alias | ACC-1,ACC-2,ACC1,ACC2,BCL2L5,BFL1,GRS,HBPA1,Bcl-2-like protein 5,Bcl2-L-5 |
| Background | Elisa Kits for: BCL2A1 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
BCL2 related protein A1 (BCL2A1) is an anti-apoptotic protein belonging to the Bcl-2 family, which plays a pivotal role in regulating apoptosis by inhibiting mitochondrial cell death pathways BCL2A1 functions by preventing the release of pro-apoptotic factors, such as cytochrome c, from mitochondria, thus blocking the activation of caspases and preventing cell death Its expression is often induced under stress conditions, such as oxidative stress and inflammatory stimuli, to protect cells from apoptosis BCL2A1 has been implicated in various cancers, where its overexpression allows tumor cells to evade apoptosis, promoting tumor survival and metastasis Additionally, BCL2A1 has a role in regulating immune cell function, particularly in maintaining the survival of B cells and T cells under stress Dysregulation of BCL2A1 contributes to immune system dysfunction and resistance to chemotherapy in cancer therapy, making it a potential target for therapeutic interventions aimed at promoting cell death in cancer cells
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