Human Bcl2 Associated Athanogene 3 (BAG3) CLIA Kit
643.5€ (96 tests)
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name
Human Bcl2 Associated Athanogene 3 (BAG3) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx195225
tested applications
CLIA
Description
Human Bcl2 Associated Athanogene 3 (BAG3) Chemiluminescent Immunoassay (CLIA) Kit is a Chemiluminescent Immunoassay (CLIA) kit against Bcl2 Associated Athanogene 3 (BAG3).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | Bcl2 Associated Athanogene 3 (BAG3) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 31.2 pg/ml - 2000 pg/ml |
| Sensitivity | 18.8 pg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Serum, plasma and other biological fluids. |
| Availability | Shipped within 5-12 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | BAG-3,BIS,CAIR-1,MFM6,Bcl-2-associated athanogene 3,Bcl-2-binding protein Bis,BAG family molecular chaperone regulator 3 |
| Background | CLIA Kits BAG3 |
| Status | RUO |
| Note | The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
BAG cochaperone 3 (BAG3) is a member of the BAG family of cochaperones that interacts with heat shock proteins like HSP70 and HSP90 to regulate cellular protein folding, stress responses, and protein degradation BAG3 is essential for the proper function of the cell’s proteostasis network, contributing to the maintenance of protein quality under stress conditions It plays a significant role in the regulation of apoptosis, autophagy, and cell survival, particularly in response to oxidative stress and heat shock conditions BAG3 is involved in the stabilization of key survival proteins, making it important for promoting cell survival during cellular stress It also has a role in skeletal muscle function and heart tissue maintenance, where its dysregulation contributes to diseases such as cardiomyopathy and muscle wasting disorders BAG3 has been implicated in cancer, where its overexpression promotes tumor cell survival, resistance to chemotherapy, and metastasis Studies suggest that BAG3 influences cytoskeletal dynamics and cellular motility, making it a key factor in cell migration and tissue remodeling
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