Human BCL2 Associated Athanogene 2 (BAG2) Protein
338€ (10 µg)
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935106861
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name
Human BCL2 Associated Athanogene 2 (BAG2) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx692799
tested applications
SDS-PAGE
Description
Human Bcl-2-Associated Athanogene 1 Protein is a recombinant protein from Human produced in E. coli. Recombinant Human BAG Family Molecular Chaperone Regulator 2 is produced by our E.coli expression system and the target gene encoding Met1-Asn211 is expressed with a 6His tag at the N-terminus.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Bcl-2-Associated Athanogene 1 |
| Host | E. coli |
| Origin | Human |
| Observed MW | Molecular Weight: 25.9 kDa Sequence Fragment: Met1-Asn211 Tag: N-terminal 6 His tag |
| Expression | Recombinant |
| Purity | > 90% (SDS-PAGE) |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Form | Lyophilized |
| Tested Applications | SDS-PAGE |
| Buffer | 20mM TrisHCl, 150mM NaCl, pH 8.0. |
| Availability | Shipped within 5-15 working days. |
| Storage | Store at < -20°C. |
| Dry Ice | No |
| UniProt ID | O95816 |
| Alias | BAG-2,dJ417I1.2,Bcl-2-associated athanogene 2,BAG family molecular chaperone regulator 2 |
| Background | Protein BAG2 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
BAG cochaperone 2 (BAG2) is a protein that functions as a cochaperone for heat shock proteins (HSPs), particularly HSP70, to regulate protein folding and degradation BAG2 plays a key role in controlling the cellular stress response by modulating protein homeostasis under stress conditions It interacts with misfolded proteins and assists in their proper folding or directs them for proteasomal degradation through the ubiquitin-proteasome pathway BAG2 also has roles in the regulation of apoptosis, where it can influence cell survival by interacting with pro-apoptotic factors BAG2 is implicated in various diseases, including cancer, where its expression can promote tumor progression by stabilizing key oncogenic proteins and inhibiting cell death pathways Additionally, BAG2 has been linked to neurodegenerative diseases such as Parkinson's disease, where its role in protein quality control is crucial for preventing the accumulation of toxic protein aggregates Its ability to modulate protein turnover and cell survival pathways highlights BAG2 as an important player in maintaining cellular integrity and a potential target for therapeutic intervention
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