Human Basal Cell Adhesion Molecule (BCAM) Protein

Este producto es parte de BCAM - basal cell adhesion molecule
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221€ (10 µg)

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935106861
info@markelab.com
name
Human Basal Cell Adhesion Molecule (BCAM) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166711
tested applications
WB, SDS-PAGE

Description

Basal Cell Adhesion Molecule Protein is a recombinant Human protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Basal Cell Adhesion Molecule (BCAM)
Host
E. coli
Origin
Human
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 28.7 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Glu32-His257
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 95%
Size 1
10 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
500 µg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
Basal cell adhesion molecule,Lutheran blood group,AU,LU,B-CAM,CD239,MSK19,Auberger B antigen,B-CAM cell surface glycoprotein
Background
Protein BCAM
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Basal Cell Adhesion Molecule (BCAM), also known as Lu antigen or Lutheran antigen, is a type I membrane glycoprotein primarily expressed on the surface of erythrocytes (red blood cells) and other cell types, including endothelial cells and certain epithelial cells. BCAM belongs to the immunoglobulin superfamily of cell adhesion molecules (IgCAMs), which are involved in the adhesion between cells and the extracellular matrix. It is notably involved in the Lutheran blood group system, which plays an important role in blood transfusion medicine. BCAM is an important adhesion molecule that facilitates interactions between cells, as well as between cells and their extracellular matrix (ECM), thus contributing to tissue integrity and signaling processes. BCAM is critical in the endothelial cell junctions and erythrocyte adhesion to endothelial cells, thereby influencing processes like inflammation, vascular permeability, and cell migration. BCAM's expression on erythrocytes links it to important blood group antigens, which have clinical relevance in transfusion medicine, as well as in understanding the molecular mechanisms of various diseases, including autoimmune disorders, inflammatory diseases, and cancers.

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