Human BAG2 (BAG family molecular chaperone regulator 2) ELISA Kit

Product specifications

ELISA Kits

Human

Colorimetric

4 hours

Sandwich ELISA, Double Antibody

15.625-1000pg/ml

9.375pg/ml

96T

ELISA

Serum, Plasma, Cell Culture Supernatant, cell or tissue lysate, Other liquid samples

Shipped within 10-14 working days.

2-8 °C for 12 months

O95816

BAG-2,dJ417I1.2,Bcl-2-associated athanogene 2,BAG family molecular chaperone regulator 2

Elisa kits for BAG2

RUO

BAG cochaperone 2 (BAG2) is a protein that functions as a cochaperone for heat shock proteins (HSPs), particularly HSP70, to regulate protein folding and degradation BAG2 plays a key role in controlling the cellular stress response by modulating protein homeostasis under stress conditions It interacts with misfolded proteins and assists in their proper folding or directs them for proteasomal degradation through the ubiquitin-proteasome pathway BAG2 also has roles in the regulation of apoptosis, where it can influence cell survival by interacting with pro-apoptotic factors BAG2 is implicated in various diseases, including cancer, where its expression can promote tumor progression by stabilizing key oncogenic proteins and inhibiting cell death pathways Additionally, BAG2 has been linked to neurodegenerative diseases such as Parkinson's disease, where its role in protein quality control is crucial for preventing the accumulation of toxic protein aggregates Its ability to modulate protein turnover and cell survival pathways highlights BAG2 as an important player in maintaining cellular integrity and a potential target for therapeutic intervention

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