Human B-Lymphocyte Antigen CD19 (CD19) Protein

234€ (1 µg)
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935106861
info@markelab.com
name
Human B-Lymphocyte Antigen CD19 (CD19) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680180
tested applications
SDS-PAGE
Description
Human B-Lymphocyte Antigen CD19 (CD19) Protein is a recombinant protein produced in Sf9, Baculovirus cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides | 
| Immunogen Target | B-Lymphocyte Antigen CD19 (CD19) | 
| Host | Insect | 
| Origin | Human | 
| Conjugation | Unconjugated | 
| Expression | Recombinant | 
| Purity | > 85% (SDS-PAGE) | 
| Size 1 | 1 µg | 
| Size 2 | 5 µg | 
| Size 3 | 50 µg | 
| Form | Liquid | 
| Tested Applications | SDS-PAGE | 
| Availability | Shipped within 5-10 working days. | 
| Dry Ice | No | 
| Alias | B4,CVID3,B-lymphocyte antigen CD19,B-lymphocyte surface antigen B4,Differentiation antigen CD19,T-cell surface antigen Leu-12 | 
| Background | Protein CD19 | 
| Status | RUO | 
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. | 
Descripción
CD19 is a transmembrane glycoprotein primarily expressed on B cells, a subset of white blood cells responsible for producing antibodies and mediating humoral immunity. CD19 plays a crucial role in B-cell development, activation, and differentiation, making it a critical marker and regulator in the immune response. It is part of the immunoglobulin superfamily and serves as a coreceptor for the B-cell receptor (BCR), amplifying BCR-mediated signaling, which is essential for proper immune function. CD19 is expressed throughout most stages of B-cell development, from the pro-B cell stage in the bone marrow to mature B cells in peripheral tissues. This widespread expression makes it a reliable marker for identifying B cells in research and clinical settings, and it is often targeted in therapeutic strategies aimed at modulating B-cell function, such as in CAR-T cell therapy for treating B-cell malignancies.
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