Human B-Lymphocyte Antigen CD19 (CD19) Protein

234€ (1 µg)
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935106861
info@markelab.com
name
Human B-Lymphocyte Antigen CD19 (CD19) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx680180
tested applications
SDS-PAGE
Description
Human B-Lymphocyte Antigen CD19 (CD19) Protein is a recombinant protein produced in Sf9, Baculovirus cells.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Proteins and Peptides |
Immunogen Target | B-Lymphocyte Antigen CD19 (CD19) |
Host | Insect |
Origin | Human |
Conjugation | Unconjugated |
Expression | Recombinant |
Purity | > 85% (SDS-PAGE) |
Size 1 | 1 µg |
Size 2 | 5 µg |
Size 3 | 50 µg |
Form | Liquid |
Tested Applications | SDS-PAGE |
Availability | Shipped within 5-10 working days. |
Dry Ice | No |
Alias | B4,CVID3,B-lymphocyte antigen CD19,B-lymphocyte surface antigen B4,Differentiation antigen CD19,T-cell surface antigen Leu-12 |
Background | Protein CD19 |
Status | RUO |
Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
CD19 is a transmembrane glycoprotein primarily expressed on B cells, a subset of white blood cells responsible for producing antibodies and mediating humoral immunity. CD19 plays a crucial role in B-cell development, activation, and differentiation, making it a critical marker and regulator in the immune response. It is part of the immunoglobulin superfamily and serves as a coreceptor for the B-cell receptor (BCR), amplifying BCR-mediated signaling, which is essential for proper immune function. CD19 is expressed throughout most stages of B-cell development, from the pro-B cell stage in the bone marrow to mature B cells in peripheral tissues. This widespread expression makes it a reliable marker for identifying B cells in research and clinical settings, and it is often targeted in therapeutic strategies aimed at modulating B-cell function, such as in CAR-T cell therapy for treating B-cell malignancies.
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