B-Lymphocyte Antigen CD19 (CD19) Antibody

Este producto es parte de CD19 - CD19 molecule
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52€ (10 µg)

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935106861
info@markelab.com
name
B-Lymphocyte Antigen CD19 (CD19) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx012770
tested applications
ELISA, WB

Description

Rabbit polyclonal antibody against CD19 protein. Immunogen region is C-terminal.

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetB-Lymphocyte Antigen CD19 (CD19)
HostRabbit
ReactivityHuman, Mouse
Recommended DilutionWB: 1/500 - 1/3000, ELISA: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
ClonalityPolyclonal
ConjugationUnconjugated
IsotypeIgG
PurificationPurified from rabbit antiserum by affinity chromatography using epitope-specific immunogen.
Size 110 µg
Size 2100 µg
Size 3200 µg
Size 4300 µg
Size 51 mg
FormLiquid
Tested ApplicationsELISA, WB
BufferPBS (without Mg<sup>2+</sup> and Ca<sup>2+</sup>), pH 7.4, 150 mM NaCl, 0.02% sodium azide, 50% glycerol.
AvailabilityShipped within 5-10 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP15391
AliasB4,CVID3,B-lymphocyte antigen CD19,B-lymphocyte surface antigen B4,Differentiation antigen CD19,T-cell surface antigen Leu-12
BackgroundAntibody anti-CD19
StatusRUO
NoteConcentration: 1 mg/ml -

Descripción

CD19 is a transmembrane glycoprotein primarily expressed on B cells, a subset of white blood cells responsible for producing antibodies and mediating humoral immunity. CD19 plays a crucial role in B-cell development, activation, and differentiation, making it a critical marker and regulator in the immune response. It is part of the immunoglobulin superfamily and serves as a coreceptor for the B-cell receptor (BCR), amplifying BCR-mediated signaling, which is essential for proper immune function. CD19 is expressed throughout most stages of B-cell development, from the pro-B cell stage in the bone marrow to mature B cells in peripheral tissues. This widespread expression makes it a reliable marker for identifying B cells in research and clinical settings, and it is often targeted in therapeutic strategies aimed at modulating B-cell function, such as in CAR-T cell therapy for treating B-cell malignancies.

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