Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B) Antibody

Pida mas información

935106861

info@markelab.com

Precio

350€ (100 µg)

proveedor

Abbexa

reference

abx238829

Tested Applications

ELISA, WB

reactivity

Human, Mouse

status

RUO

clonality

Polyclonal

Descripción

TNFSF13B Antibody is a Rabbit Polyclonal against TNFSF13B.

Background

B-cell activating factor (BAFF), also called tumor necrosis factor ligand superfamily member 13B (TNFSF13B) and CD257, is a protein encoded by the TNFSF13B gene in humans. BAFF is also known by other names, including B Lymphocyte Stimulator (BLyS),CD257, TNF- and APOL-related leukocyte expressed ligand (TALL-1). The human BAFF protein consists of two glycosylated domains and one transmembrane domain (amino acids 48-68), and it can undergo cleavage into both membrane-bound and soluble peptide fragments. BAFF is primarily expressed in cells within the B cell lineage and serves as a potent activator of B cells. It plays a crucial role in promoting the proliferation and differentiation of B cells, making it a pivotal cytokine in the immune system's function.

Background

El factor activador de células B (BAFF), también llamado miembro 13B de la superfamilia del ligando del factor de necrosis tumoral (TNFSF13B) y CD257, es una proteína codificada por el gen TNFSF13B en humanos. BAFF también se conoce con otros nombres, incluido estimulador de linfocitos B (BLyS), CD257, y TALL-1 (APOL-related leukocyte expressed ligand). La proteína BAFF humana consta de dos dominios glicosilados y un dominio transmembrana (aminoácidos 48-68) y puede sufrir escisión en fragmentos peptídicos solubles y unidos a la membrana. BAFF se expresa principalmente en células del linaje de células B y sirve como un potente activador de las células B. Desempeña un papel crucial en la promoción de la proliferación y diferenciación de las células B, lo que la convierte en una citoquina fundamental en la función del sistema inmunológico.

Características del producto

clonality

Polyclonal

reactivity

Human, Mouse

immunogen target

Tumor Necrosis Factor Ligand Superfamily Member 13B / BAFF (TNFSF13B)

host

Rabbit

conjugation

Unconjugated

form

Liquid

tested applications

ELISA, WB

purity

≥ 95% (SDS-PAGE)

purification

Purified by immunogen affinity chromatography.

buffer

PBS, pH 7.3, with 0.02% sodium azide and 50% glycerol.

size 1

100 µg

storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

or code

TNFSF13B

dry ice

availability

Shipped within 5-12 working days.

alias

B lymphocyte stimulator,BLyS,BAFF,B-cell-activating factor

uniprot id

https://www.uniprot.org/uniprotkb/Q9Y275

gene id

https://www.ncbi.nlm.nih.gov/gene/10673

note

This product is for research use only.

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proveedor

Abbexa

reference

abx196334

Tested Applications

CLIA

reactivity

Human

status

RUO

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