Human ATP Binding Cassette Transporter C2 (ABCC2) CLIA Kit
845€ (96 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
Human ATP Binding Cassette Transporter C2 (ABCC2) CLIA Kit
category
CLIA Kits
provider
Abbexa
reference
abx494334
tested applications
CLIA
Description
Human ATP Binding Cassette Transporter C2 (ABCC2) Chemiluminescent Immunoassay (CLIA) Kit is a Sandwich Chemiluminescent Immunoassay (CLIA) Kit for use with Tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | CLIA Kits |
| Immunogen Target | ATP Binding Cassette Transporter C2 (ABCC2) |
| Reactivity | Human |
| Detection Method | Chemiluminescent |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.156 ng/ml - 10 ng/ml |
| Sensitivity | < 0.067 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | CLIA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-20 working days. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| Alias | ABC30,CMOAT,DJS,MRP2,cMRP |
| Background | CLIA Kits ABCC2 |
| Status | RUO |
| Note | The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ABCC2, also known as multidrug resistance-associated protein 2 (MRP2), is an ATP-binding cassette transporter primarily expressed on the apical membrane of hepatocytes, where it plays a vital role in bile secretion and detoxification. ABCC2 mediates the ATP-dependent transport of conjugated bilirubin, xenobiotics, and drug metabolites into bile, contributing to the excretion of potentially harmful compounds. It is also expressed in other tissues, such as the kidney and intestine, where it supports renal and intestinal excretion. Mutations in ABCC2 are associated with Dubin-Johnson syndrome, a rare inherited disorder characterized by impaired bilirubin transport and conjugated hyperbilirubinemia. ABCC2’s role in drug efflux and detoxification makes it a significant player in drug pharmacokinetics, impacting drug absorption, distribution, and elimination.
Related Products
ATP Binding Cassette Transporter C2 (ABCC2) Antibody
ATP Binding Cassette Transporter C2 (ABCC2) Antibody is a Rabbit Polyclonal Antibody against ATP Binding Cassette Transporter C2 (ABCC2).
Ver Producto
Canalicular Multispecific Organic Anion Transporter 1 (ABCC2) Antibody
MRP2 Antibody is a Rabbit Polyclonal antibody against MRP2.
Ver Producto
ATP Binding Cassette Transporter C2 (ABCC2) Antibody
Rabbit polyclonal antibody against ATP Binding Cassette Transporter C2 (ABCC2) protein. Immunogen region is Internal.
Ver Producto