Human ATP Binding Cassette Transporter C11 (ABCC11) ELISA Kit
715€ (96 tests)
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Name
Human ATP Binding Cassette Transporter C11 (ABCC11) ELISA Kit
Category
ELISA Kits
Provider
Abbexa
Reference
abx150502
Tested Applications
ELISA
Description
Human ATP Binding Cassette Transporter C11 (ABCC11) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ATP Binding Cassette Transporter C11 (ABCC11) concentrations in tissue homogenates, cell lysates and other biological fluids. This assay has high sensitivity and excellent specificity for detection of ATP Binding Cassette Transporter C11 (ABCC11)
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | ELISA Kits |
| Immunogen Target | ATP Binding Cassette Transporter C11 (ABCC11) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.312 ng/ml - 20 ng/ml |
| Sensitivity | < 0.11 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Standard Form: Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-7 working days. |
| Storage | Shipped at 4°C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q96J66 |
| Alias | EWWD,MRP8,WW |
| Background | Elisa Kits for: ABCC11 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR THERAPEUTIC PROCEDURES. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. The stability of the kit is determined by the rate of activity loss. The loss rate is less than 5% within the expiration date under appropriate storage conditions. To minimize performance fluctuations, operation procedures and lab conditions should be strictly controlled. It is also strongly suggested that the whole assay is performed by the same user throughout. |
Background
ATP-binding cassette subfamily C member 11 (ABCC11), also known as multidrug resistance-associated protein 8 (MRP8), is an ATP-dependent transporter involved in the efflux of various organic anions, including bile acids, cyclic nucleotides, and conjugated steroid hormones. It is highly expressed in apocrine glands, liver, and breast tissue, playing a role in physiological processes like bile acid secretion and earwax type determination. ABCC11 has clinical significance in drug transport and metabolism, with variants linked to differences in drug sensitivity and cancer susceptibility. Mutations in ABCC11 are associated with traits like dry vs. wet earwax and body odor. It has two transmembrane and two nucleotide-binding domains typical of ABC transporters.
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