Human ATP Binding Cassette Transporter A13 (ABCA13) ELISA Kit
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935106861
info@markelab.com
Precio
687.5€ (96 tests)
Elisa Kits ABCA13
proveedor
Abbexareference
abx259054Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human ATP Binding Cassette Transporter A13 (ABCA13) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ATP Binding Cassette Transporter A13 (ABCA13) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ABCA13 (ATP-binding cassette subfamily A member 13) is a member of the ATP-binding cassette (ABC) transporter superfamily, a large group of proteins that facilitate the transport of various substrates across cellular membranes. ABCA13, encoded by the ABCA13 gene on chromosome 7p12, is the largest known ABC transporter, with a coding sequence of over 5000 amino acids. Although the precise substrates transported by ABCA13 remain to be fully elucidated, its expression in neural and psychiatric contexts has drawn attention to its potential role in the central nervous system. Emerging studies suggest its involvement in lipid transport, vesicle trafficking, and membrane organization. ABCA13 is predominantly expressed in the brain, particularly in regions associated with neural activity, such as the hippocampus, cortex, and striatum. It has also been detected in other tissues, including the lungs and liver, albeit at lower levels. Dysregulation of ABCA13 has been implicated in neuropsychiatric conditions, such as schizophrenia, bipolar disorder, and depression.
Características del producto
category
ELISA Kits
immunogen target
ATP Binding Cassette Transporter A13 (ABCA13)
reactivity
Human
test range
78.125 pg/ml - 5000 pg/ml
sensitivity
46.875 pg/ml
assay type
Sandwich
assay data
Quantitative
detection method
Colorimetric
sample type
Tissue homogenates,Cell lysates,Other biological fluids
size 1
96 tests
alias
ATP-binding cassettE sub-family A (ABC1) member 13
storage
Enviado a 4 °C. Una vez recibido, almacene el kit de acuerdo con las instrucciones citadas en el manual del kit
or code
ABCA13
dry ice
No
uniprot id
note
This product is for research use only. <p></p> The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. <p></p> Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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