Human ATP Binding Cassette Subfamily G Member 4 (ABCG4) Protein
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Description
Human ABCG4 Protein is a recombinant Human protein produced in a Prokaryotic expression system (E. coli).
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Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | ATP Binding Cassette Subfamily G Member 4 (ABCG4) |
| Host | E. coli |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 30.7 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Val59-Thr301 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q9H172 |
| Alias | WHITE2 |
| Background | Protein ABCG4 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ABCG4 is a member of the ATP-binding cassette (ABC) transporter family, subfamily G, primarily expressed in the brain, macrophages, and hematopoietic stem cells. This protein plays a key role in cellular lipid homeostasis, particularly in cholesterol and phospholipid transport. It is involved in maintaining membrane lipid composition and may contribute to processes like neuroprotection and immune cell function. Dysfunction or aberrant regulation of ABCG4 is implicated in lipid-related disorders and neurological diseases. Understanding its precise role is critical for exploring its therapeutic potential in metabolic and neurodegenerative conditions.
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