Human Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 1 (ACAP1) ELISA Kit
715€ (96 tests)
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935106861
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name
Human Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 1 (ACAP1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385573
tested applications
ELISA
Description
Human Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 1 (ACAP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ACAP1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 1 (ACAP1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.188 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is 6 months. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q15027 |
| Gene ID | 9744 |
| OMIM | 607763 |
| Alias | CENTB1,Centaurin beta 1 |
| Background | Elisa kits for ACAP1 |
| Status | RUO |
| Note | Validity: The validity for this kit is 6 months. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
ACAP1 is a multifunctional protein that acts as a GTPase-activating protein (GAP) for ADP-ribosylation factors (Arfs), small GTP-binding proteins involved in vesicle trafficking and membrane dynamics. It contains a pleckstrin homology (PH) domain, ankyrin repeats, and a coiled-coil region, enabling interactions with phospholipids and proteins. ACAP1 is involved in clathrin-mediated endocytosis and recycling of membrane proteins like integrins and nutrient receptors, regulating cellular adhesion, migration, and nutrient uptake. It plays a significant role in immune and migrating cells by recycling surface proteins critical for cellular responses. Dysregulation of ACAP1 has been linked to impaired membrane trafficking, contributing to diseases such as cancer and immune disorders.
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