Human Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 1 (ACAP1) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ACAP1
proveedor
Abbexareference
abx385573Tested Applications
ELISAreactivity
Humanstatus
RUOclonality
Descripción
Human Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 1 (ACAP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ACAP1 concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ACAP1 is a multifunctional protein that acts as a GTPase-activating protein (GAP) for ADP-ribosylation factors (Arfs), small GTP-binding proteins involved in vesicle trafficking and membrane dynamics. It contains a pleckstrin homology (PH) domain, ankyrin repeats, and a coiled-coil region, enabling interactions with phospholipids and proteins. ACAP1 is involved in clathrin-mediated endocytosis and recycling of membrane proteins like integrins and nutrient receptors, regulating cellular adhesion, migration, and nutrient uptake. It plays a significant role in immune and migrating cells by recycling surface proteins critical for cellular responses. Dysregulation of ACAP1 has been linked to impaired membrane trafficking, contributing to diseases such as cancer and immune disorders.
Características del producto
category
ELISA Kits
immunogen target
Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 1 (ACAP1)
reactivity
Human
test range
0.313 ng/ml - 20 ng/ml
sensitivity
< 0.188 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
CENTB1,Centaurin beta 1
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ACAP1
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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