Human Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 1 (ACAP1) ELISA Kit

Este producto es parte de ACAP - Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein
Human Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 1 (ACAP1) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for ACAP1

proveedor

Abbexa

reference

abx385573

Tested Applications

ELISA

reactivity

Human

status

RUO

clonality

Descripción

Human Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 1 (ACAP1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human ACAP1 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

ACAP1 is a multifunctional protein that acts as a GTPase-activating protein (GAP) for ADP-ribosylation factors (Arfs), small GTP-binding proteins involved in vesicle trafficking and membrane dynamics. It contains a pleckstrin homology (PH) domain, ankyrin repeats, and a coiled-coil region, enabling interactions with phospholipids and proteins. ACAP1 is involved in clathrin-mediated endocytosis and recycling of membrane proteins like integrins and nutrient receptors, regulating cellular adhesion, migration, and nutrient uptake. It plays a significant role in immune and migrating cells by recycling surface proteins critical for cellular responses. Dysregulation of ACAP1 has been linked to impaired membrane trafficking, contributing to diseases such as cancer and immune disorders.

Características del producto

category

ELISA Kits


immunogen target

Arf-GAP With Coiled-Coil, ANK Repeat And PH Domain Containing Protein 1 (ACAP1)


reactivity

Human


test range

0.313 ng/ml - 20 ng/ml


sensitivity

< 0.188 ng/ml


assay type

Sandwich


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

CENTB1,Centaurin beta 1


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

ACAP1


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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