Human Archaelysin Family Metallopeptidase 1 (AMZ1) ELISA Kit
715€ (96 tests)
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name
Human Archaelysin Family Metallopeptidase 1 (AMZ1) ELISA Kit
category
ELISA Kits
provider
Abbexa
reference
abx385736
tested applications
ELISA
Description
Human Archaelysin Family Metallopeptidase 1 (AMZ1) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Human Archaemetzincin 1 (AMZ1) concentrations in tissue homogenates, cell lysates and other biological fluids.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | ELISA Kits |
| Immunogen Target | Archaelysin Family Metallopeptidase 1 (AMZ1) |
| Reactivity | Human |
| Detection Method | Colorimetric |
| Assay Data | Quantitative |
| Assay Type | Sandwich |
| Test Range | 0.313 ng/ml - 20 ng/ml |
| Sensitivity | < 0.19 ng/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Size 1 | 96 tests |
| Size 2 | 5 × 96 tests |
| Size 3 | 10 × 96 tests |
| Form | Lyophilized |
| Tested Applications | ELISA |
| Sample Type | Tissue homogenates, cell lysates and other biological fluids. |
| Availability | Shipped within 5-12 working days. The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. |
| Storage | Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual. |
| Dry Ice | No |
| UniProt ID | Q400G9 |
| Gene ID | 155185 |
| OMIM | 615168 |
| Alias | AMZ1 |
| Background | Elisa kits for AMZ1 |
| Status | RUO |
| Note | Validity: The validity for this kit is at least 6 months. Up to 12 months validity can be provided on request. This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein. |
Descripción
AMZ1 is a member of the archaelysin family of zinc-dependent metallopeptidases, enzymes that cleave peptide bonds in a variety of substrates. AMZ1 is expressed in multiple tissues, where it functions in protein turnover, extracellular matrix remodeling, and cellular signaling. As a metallopeptidase, AMZ1 requires a zinc ion for catalytic activity, which stabilizes the enzyme's active site and facilitates hydrolysis of peptide bonds. AMZ1 is thought to participate in processes such as tissue development, wound healing, and immune responses by regulating extracellular matrix components and growth factors. Dysregulation of AMZ1 activity has been implicated in pathological processes such as fibrosis, inflammation, and tumor progression, where excessive matrix degradation or improper protease activity contributes to disease. AMZ1's ability to cleave a broad range of substrates highlights its importance in maintaining proteolytic balance, tissue homeostasis, and intercellular communication.
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AMZ1 antibody
AMZ1, also named as KIAA1950, is a new human Zinc metalloproteases. It exhibits aminopeptidase activity against neurogranin in vitro. AMZ1 does not hydrolyze angiotensin-2. It is mainly detected in liver and heart. AMZ1 has some isoforms with MW 55 kDa, 33 kDa, 30 kDa and 28 kDa.
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