Human Serotonin N-Acetyltransferase (AANAT) Protein
221€ (10 µg)
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Name
Human Serotonin N-Acetyltransferase (AANAT) Protein
Category
Proteins and Peptides
Provider
Abbexa
Reference
abx652586
Tested Applications
WB, SDS-PAGE
Description
Human Arylalkylamine-N-Acetyltransferase (AANAT) Protein is a recombinant Human protein expressed in E. coli.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Proteins and Peptides |
| Immunogen Target | Serotonin N-Acetyltransferase (AANAT) |
| Host | E. coli |
| Assay Type | Activity: Not tested Sequence Fragment: Met1-Cys207 Tag: N-terminal His tag |
| Origin | Human |
| Conjugation | Unconjugated |
| Observed MW | Calculated MW: 27 kDa Observed MW (SDS-PAGE): 25 kDa |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 10 µg |
| Size 2 | 50 µg |
| Size 3 | 100 µg |
| Size 4 | 200 µg |
| Size 5 | 500 µg |
| Form | Lyophilized |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store lyophilized form at 2-8°C for up to 1 month. For longer periods, store lyophilized or liquid at -80°C. Avoid repeated freeze–thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q16613 |
| Alias | AA-NAT,Nat4,SNAT |
| Background | Protein AANAT |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. Concentration: Prior to lyophilization: 200 µg/ml |
Background
AANAT, ,Aralkylamine N-acetyltransferase (AANAT), also known as arylalkylamine N-acetyltransferase is an enzyme encoded by the AANAT gene. It plays a critical role in the biosynthesis of melatonin, a hormone involved in regulating the circadian rhythm and other physiological processes. AANAT catalyzes the transfer of an acetyl group from acetyl-CoA to serotonin, the precursor molecule of melatonin, fundamental in coordination of daily and seasonal rhythms. Activity may increase 10- to 100-fold at night, causing an increase in the production and release of melatonin. Dysregulation of AANAT activity or melatonin synthesis can have implications for sleep disorders, circadian rhythm disorders, and psychiatric conditions
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