Human Serotonin N-Acetyltransferase (AANAT) Protein

Este producto es parte de AANAT - Aralkylamine N-Acetyltransferase
Human Serotonin N-Acetyltransferase (AANAT) Protein

Pida mas información

935106861

info@markelab.com

Precio

221€ (10 µg)

Protein AANAT

proveedor

Abbexa

reference

abx652586

Tested Applications

WB, SDS-PAGE

reactivity

status

RUO

clonality

Descripción

Human Arylalkylamine-N-Acetyltransferase (AANAT) Protein is a Recombinant Human protein expressed in E. coli.


Background

AANAT, ,Aralkylamine N-acetyltransferase (AANAT), also known as arylalkylamine N-acetyltransferase is an enzyme encoded by the AANAT gene. It plays a critical role in the biosynthesis of melatonin, a hormone involved in regulating the circadian rhythm and other physiological processes. AANAT catalyzes the transfer of an acetyl group from acetyl-CoA to serotonin, the precursor molecule of melatonin, fundamental in coordination of daily and seasonal rhythms. Activity may increase 10- to 100-fold at night, causing an increase in the production and release of melatonin. Dysregulation of AANAT activity or melatonin synthesis can have implications for sleep disorders, circadian rhythm disorders, and psychiatric conditions

Características del producto

category

Proteins and Peptides


origin

Human


host

E. coli


immunogen target

Serotonin N-Acetyltransferase (AANAT)


host

E. coli


conjugation

Unconjugated


form

Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.


tested applications

WB, SDS-PAGE


size 1

10 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

500 µg


observerd MW

Molecular Weight: Calculated MW: 27 kDa Observed MW (SDS-PAGE): 25 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Cys207 Tag: N-terminal His tag


expression

Recombinant


purity

> 95%


buffer

Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 0.01% Sarcosyl, 5% Trehalose.


storage

Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.


or code

AANAT


dry ice

No


availability

Shipped within 1-2 months.


alias

AA-NAT,Nat4,SNAT


note

This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use.


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