Family main features
AANAT, ,Aralkylamine N-acetyltransferase (AANAT), also known as arylalkylamine N-acetyltransferase is an enzyme encoded by the AANAT gene. It plays a critical role in the biosynthesis of melatonin, a hormone involved in regulating the circadian rhythm and other physiological processes. AANAT catalyzes the transfer of an acetyl group from acetyl-CoA to serotonin, the precursor molecule of melatonin, fundamental in coordination of daily and seasonal rhythms. Activity may increase 10- to 100-fold at night, causing an increase in the production and release of melatonin. Dysregulation of AANAT activity or melatonin synthesis can have implications for sleep disorders, circadian rhythm disorders, and psychiatric conditions
AANAT is a soluble enzyme that belongs to the GNAT (GCN5-related N-acetyltransferase) superfamily of enzymes. It consists of a catalytic domain that binds both the acetyl-CoA cofactor and the substrate serotonin. AANAT undergoes conformational changes upon substrate binding, facilitating the acetylation reaction.
AANAT is classified as an arylalkylamine N-acetyltransferase and is part of the GNAT superfamily. While there are no known subtypes of AANAT in humans, its enzymatic activity is conserved across various species, from bacteria to mammals.
Aralkylamine N-Acetyltransferase(AANAT)
AA-NAT,Nat4,SNAT
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Esta página contiene 19 reactivos de las marcas (Abbexa, FineTest) que se corresponden con tu busqueda
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provider | Code | reference | name | reactivity | sample type | assay type | test range | sensitivity | price | size 1 | uniprot id | status |
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Abbexa | AANAT | abx518887 | Cow Serotonin N-Acetyltransferase (AANAT) ELISA Kit | Cow | Tissue homogenates,Cell lysates,Other biological fluids | 0.625 ng/ml - 40 ng/ml | < 0.32 ng/ml | 687.5 | 96 tests | O02785 | RUO | |
FineTest | AANAT | EH2008 | Human AANAT(Serotonin N-acetyltransferase) ELISA Kit | human | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.156-10ng/ml | 96T | Q16613 | RUO | ||
Abbexa | AANAT | abx493274 | Human Serotonin N-Acetyltransferase (AANAT) CLIA Kit | Human | Tissue homogenates, cell lysates and other biological fluids. | Sandwich | 0.78 ng/ml - 50 ng/ml | < 0.35 ng/ml | 812.5 | 96 tests | RUO | |
Abbexa | AANAT | abx156746 | Human Serotonin N-Acetyltransferase (AANAT) ELISA Kit | Human | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.78 ng/ml - 50 ng/ml | < 0.35 ng/ml | 618.75 | 96 tests | RUO | |
Abbexa | AANAT | abx518890 | Mouse Serotonin N-Acetyltransferase (AANAT) ELISA Kit | Mouse | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.19 ng/ml | 687.5 | 96 tests | O88816 | RUO |
FineTest | AANAT | ER0615 | Rat Aanat(Serotonin N-acetyltransferase) ELISA Kit | rat | Serum,Plasma,Tissue homogenates,Other biological fluids | Sandwich ELISA, Double Antibody | 0.313-20ng/ml | 96T | Q64666 | RUO | ||
Abbexa | AANAT | abx256590 | Rat Serotonin N-Acetyltransferase (AANAT) ELISA Kit | Rat | Tissue homogenates,Cell lysates,Other biological fluids | Sandwich | 0.312 ng/ml - 20 ng/ml | < 0.188 ng/ml | 687.5 | 96 tests | Q64666 | RUO |
provider | Code | reference | name | reactivity | clonality | host | immunogen target | isotype | conjugation | tested applications | price | size 1 | uniprot id | status |
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FineTest | AANAT | FNab00020 | anti- AANAT antibody | human | polyclonal | Rabbit | arylalkylamine N-acetyltransferase | IgG | Unconjugated | ELISA, WB, IHC | 100µg | Q16613 | RUO | |
Abbexa | AANAT | abx034449 | Serotonin N-Acetyltransferase (AANAT) Antibody | Human | Polyclonal | Rabbit | Serotonin N-Acetyltransferase (AANAT) | Unconjugated | ELISA, WB | 281.25 | 80 µl | Q16613 | RUO | |
Abbexa | AANAT | abx337649 | Serotonin N-Acetyltransferase (AANAT) Antibody (HRP) | Human | Polyclonal | Rabbit | Serotonin N-Acetyltransferase (AANAT) | HRP | ELISA | 162.5 | 20 µg | Q16613 | RUO | |
Abbexa | AANAT | abx337650 | Serotonin N-Acetyltransferase (AANAT) Antibody (FITC) | Human | Polyclonal | Rabbit | Serotonin N-Acetyltransferase (AANAT) | FITC | 162.5 | 20 µg | Q16613 | RUO | ||
Abbexa | AANAT | abx337651 | Serotonin N-Acetyltransferase (AANAT) Antibody (Biotin) | Human | Polyclonal | Rabbit | Serotonin N-Acetyltransferase (AANAT) | Biotin | ELISA | 162.5 | 20 µg | Q16613 | RUO | |
Abbexa | AANAT | abx126816 | Serotonin N-Acetyltransferase (AANAT) Antibody | Human | Polyclonal | Rabbit | Serotonin N-Acetyltransferase (AANAT) | Unconjugated | WB | 175 | 20 µl | Q16613 | RUO | |
Abbexa | AANAT | abx338383 | Serotonin N-Acetyltransferase (AANAT) Antibody | Human | Polyclonal | Rabbit | Serotonin N-Acetyltransferase (AANAT) | Unconjugated | ELISA, WB, IF/ICC | 162.5 | 20 µg | Q16613 | RUO | |
Abbexa | AANAT | abx214540 | Serotonin N-Acetyltransferase (AANAT) Antibody | Human | Polyclonal | Rabbit | Serotonin N-Acetyltransferase (AANAT) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q16613 | RUO | |
Abbexa | AANAT | abx214539 | Serotonin N-Acetyltransferase (AANAT) Antibody | Human | Polyclonal | Rabbit | Serotonin N-Acetyltransferase (AANAT) | Unconjugated | ELISA, IHC | 250 | 50 µl | Q16613 | RUO | |
Abbexa | AANAT | abx230020 | Serotonin N-Acetyltransferase (AANAT) Antibody | Human | Polyclonal | Rabbit | Serotonin N-Acetyltransferase (AANAT) | Unconjugated | ELISA, WB, IHC | 350 | 100 µg | Q16613 | RUO |
provider | Code | reference | name | origin | expression | host | conjugation | tested applications | price | size 1 | uniprot id | status |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Abbexa | AANAT | abx652586 | Human Serotonin N-Acetyltransferase (AANAT) Protein | Human | Recombinant | E. coli | Unconjugated | WB, SDS-PAGE | 212.5 | 10 µg | Q16613 | RUO |
FineTest | AANAT | P5879 | Recombinant Human AANAT | Human | Recombinant | E.Coli | Western Blot,ELISA | 50μg | Q16613 | RUO |
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